Aurachin E

Aurachin E

SCHEMBL29392647

CC(C)=CCC/C(C)=C/CC/C(C)=C/Cc1c(C)n2c(=O)[nH]c3cccc(c1=O)c32

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ VKORC1 Q9BQB6 1/20 0.48
▸ MAOA P21397 1/20 0.43
▸ PGR P06401 1/20 0.41
▸ HTR1A P08908 1/20 0.41
▸ ADORA3 P0DMS8 1/20 0.41
▸ MAPT P10636 1/20 0.41
▸ PTGS1 P23219 1/20 0.41
▸ PDE4A P27815 1/20 0.41
▸ MAPK1 P28482 1/20 0.41
▸ DRD3 P35462 1/20 0.41
▸ SNCA P37840 1/20 0.41
▸ PDE3A Q14432 1/20 0.41
▸ PTPN1 P18031 2/20 0.40
▸ BACE1 P56817 2/20 0.40
▸ LMNA P02545 1/20 0.39
▸ MAOB P27338 7/20 0.38
▸ APP P05067 3/20 0.38
▸ CTSV O60911 1/20 0.38
▸ SLC2A1 P11166 1/20 0.38
▸ ALOX15 P16050 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Aurachin E SCHEMBL29885181 1.00 VKORC1 (0.48) VKORC1MAOAPGRHTR1AADORA3
Aurachin D SCHEMBL15094902 0.77 SLC2A1 (0.64) VKORC1MAOAPGRHTR1AADORA3
Aurachin D SCHEMBL16552860 0.77 SLC2A1 (0.64) VKORC1MAOAPGRHTR1AADORA3
Aurachin D SCHEMBL29456185 0.77 SLC2A1 (0.64) VKORC1MAOAPGRHTR1AADORA3
Aurachin C SCHEMBL16553028 0.74 VKORC1 (0.54) VKORC1MAOAPGRHTR1AADORA3
Aurachin C SCHEMBL15094711 0.74 VKORC1 (0.54) VKORC1MAOAPGRHTR1AADORA3
SCHEMBL14519803 0.69 CYP2D6 (0.53) VKORC1MAOAPGRHTR1AADORA3
SCHEMBL16431075 0.69 CYP2D6 (0.53) VKORC1MAOAPGRHTR1AADORA3
SCHEMBL9597639 0.68 VKORC1 (0.51) VKORC1MAOAPGRHTR1AADORA3
SCHEMBL20851833 0.66 VKORC1 (0.57) VKORC1PGRHTR1AADORA3MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025215072-A1 CLASS I LANTHIPEPTIDES WITH ANTI-VIRAL FUNCTION Institut National de la Santé et de la Recherche Médicale (FR) 2025-10-16 — — WO disclosed
US-11932891-B2 Co-culture of myxobacteria and Bacillus for enhanced metabolite production LOCUS SOLUTIONS IPCO, LLC (US) 2024-03-19 — — US disclosed
CN-115916958-A Bacillus strain applied to agriculture, livestock health and environmental protection 轨迹IP有限责任公司 2023-04-04 — — CN disclosed
EP-4136210-A1 BACILLUS STRAIN FOR APPLICATIONS IN AGRICULTURE, LIVESTOCK HEALTH AND ENVIRONMENTAL PROTECTION Locus IP Company, LLC (US) 2023-02-22 — — EP disclosed
US-20230029570-A1 Bacillus Strain for Applications in Agriculture, Livestock Health and Environmental Protection LOCUS AGRICULTURAL SOLUTIONS, LLC 2023-02-02 — — US disclosed
US-20220364126-A1 Three-Vessel Reactor System for Producing Microbial Biosurfactants and Other Metabolites LOCUS SOLUTIONS, LLC 2022-11-17 — — US disclosed
EP-4051774-A1 THREE-VESSEL REACTOR SYSTEM FOR PRODUCING MICROBIAL BIOSURFACTANTS AND OTHER METABOLITES Locus IP Company, LLC (US) 2022-09-07 — — EP disclosed
US-11421223-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2022-08-23 — — US disclosed
US-20220243241-A1 Co-Culture of Myxobacteria and Pseudomonas for Enhanced Production of Biosurfactants and Other Metabolites LOCUS SOLUTIONS, LLC 2022-08-04 — — US disclosed
US-20220211047-A1 Broad Spectrum Biopesticides Comprising Beneficial Microorganisms LOCUS OIL HOLDING, LLC, 2022-07-07 — — US disclosed
US-11377585-B2 Co-cultivation of a myxobacterium and acinetobacter for enhanced production of emulsan LOCUS IP COMPANY, LLC (US) 2022-07-05 — — US disclosed
US-20220154238-A1 Co-Culture of Myxobacteria and Bacillus for Enhanced Metabolite Production LOCUS OIL HOLDING, LLC, 2022-05-19 — — US disclosed
EP-3987046-A1 CO-CULTIVATION OF A MYXOBACTERIUM AND ACINETOBACTER FOR ENHANCED PRODUCTION OF EMULSAN Locus IP Company, LLC (US) 2022-04-27 — — EP disclosed
EP-3983552-A1 CO-CULTURE OF MYXOBACTERIA AND PSEUDOMONAS FOR ENHANCED PRODUCTION OF BIOSURFACTANTS AND OTHER METABOLITES Locus IP Company, LLC (US) 2022-04-20 — — EP disclosed
US-20220099672-A1 Method for Treating and/or Preventing Bacteriophage Lysis During Fermentation LOCUS SOLUTIONS, LLC 2022-03-31 — — US disclosed
US-20220062961-A1 Use of Peanut Hearts as a Fermentation Biostimulant LOCUS BIO-ENERGY SOLUTIONS, LLC 2022-03-03 — — US disclosed
EP-3947706-A1 CO-CULTURE OF MYXOBACTERIA AND BACILLUS FOR ENHANCED METABOLITE PRODUCTION Locus IP Company, LLC (US) 2022-02-09 — — EP disclosed
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