SCHEMBL29392847

SCHEMBL29392847

C[C@@H](O)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)CN)[C@@H](C)O)C(=O)O

nearest known ligand 0.69

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ SLC6A2 P23975 1/20 0.60
▸ OPRD1 P41143 5/20 0.56
▸ NTSR1 P30989 5/20 0.56
▸ NTSR2 O95665 3/20 0.54
▸ OPRM1 P35372 2/20 0.54
▸ OPRK1 P41145 1/20 0.54
▸ SORT1 Q99523 2/20 0.53
▸ F2 P00734 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30558098 0.94 SLC6A2 (0.67) SLC6A2OPRD1NTSR1NTSR2OPRM1
SCHEMBL29530789 0.93 SLC6A2 (0.70) SLC6A2OPRD1NTSR1NTSR2OPRM1
SCHEMBL29530950 0.93 SLC6A2 (0.70) SLC6A2OPRD1NTSR1NTSR2OPRM1
SCHEMBL29440860 0.89 SLC6A2 (0.62) SLC6A2OPRD1NTSR1NTSR2OPRM1
SCHEMBL29531192 0.89 SLC6A2 (0.63) SLC6A2OPRD1NTSR1NTSR2OPRM1
SCHEMBL31410882 0.87 SLC6A2 (0.67) SLC6A2OPRD1NTSR1NTSR2OPRM1
SCHEMBL29402848 0.87 SLC6A2 (0.77) SLC6A2OPRD1NTSR1NTSR2OPRM1
SCHEMBL29353395 0.87 SLC6A2 (0.77) SLC6A2OPRD1NTSR1NTSR2OPRM1
SCHEMBL30558096 0.87 SLC6A2 (0.60) SLC6A2OPRD1OPRM1OPRK1
SCHEMBL32691451 0.86 SLC6A2 (0.59) SLC6A2OPRD1NTSR1NTSR2OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3956355-B1 STABILIZATION OF PRANDIAL OR BASAL INSULIN ANALOGUES BY AN INTERNAL DISELENIDE BRIDGE UNIV INDIANA TRUSTEES (US) 2025-11-26 — — EP disclosed
US-20220144915-A1 STABILIZATION OF PRANDIAL OR BASAL INSULIN ANALOGUES BY AN INTERNAL DISELENIDE BRIDGE NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2022-05-12 — — US disclosed
EP-3956355-A1 STABILIZATION OF PRANDIAL OR BASAL INSULIN ANALOGUES BY AN INTERNAL DISELENIDE BRIDGE The Trustees of Indiana University (US) 2022-02-23 — — EP disclosed
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