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SCHEMBL29393136

SCHEMBL29393136

CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CO)O[C@@](O[C@H](CO)[C@@H](O)[C@@H]2O[C@@](O[C@H](CO)[C@@H](O)[C@@H]3O[C@@](O[C@@H]4[C@@H](O)[C@H](O)O[C@H](CO)[C@@H]4O)(C(=O)O)C[C@H](O)[C@H]3NC(C)=O)(C(=O)O)C[C@H](O)[C@H]2NC(C)=O)(C(=O)O)C[C@@H]1O

nearest known ligand 0.66

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ SIGLEC7 Q9Y286 6/20 0.66
▸ SELP P16109 2/20 0.60
▸ SELL P14151 1/20 0.60
▸ MAG P20916 9/20 0.58
▸ NANP Q8TBE9 1/20 0.48
▸ SELE P16581 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29454806 1.00 SIGLEC7 (0.66) SIGLEC7SELPSELLMAGNANP
SCHEMBL29355980 1.00 SIGLEC7 (0.66) SIGLEC7SELPSELLMAGNANP
SCHEMBL30439275 0.96 SIGLEC7 (0.62) SIGLEC7SELPSELLMAGNANP
SCHEMBL30439269 0.96 SIGLEC7 (0.62) SIGLEC7SELPSELLMAGNANP
SCHEMBL29356627 0.95 SELP (0.62) SIGLEC7SELPSELLMAGNANP
SCHEMBL29396615 0.95 SELP (0.62) SIGLEC7SELPSELLMAGNANP
SCHEMBL17300130 0.95 SELP (0.62) SIGLEC7SELPSELLMAGNANP
SCHEMBL31716489 0.93 SIGLEC7 (0.70) SIGLEC7SELPSELLMAGSELE
SCHEMBL29615820 0.92 SIGLEC7 (0.71) SIGLEC7SELPSELLMAGSELE
SCHEMBL29378134 0.92 SIGLEC7 (0.76) SIGLEC7SELPSELLMAGSELE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11359014-B2 Anti-siglec-5 antibodies and methods of use thereof ALECTOR LLC (US) 2022-06-14 — — US disclosed
US-11254743-B2 Anti-CD33 antibodies and methods of use thereof ALECTOR LLC (US) 2022-02-22 — — US disclosed
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