SCHEMBL29393232

SCHEMBL29393232

O=C(O)C=Cc1ccccc1Cl

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 2/20 0.65
HDAC8 Q9BY41 2/20 0.65
HDAC6 Q9UBN7 2/20 0.65
GSR P00390 1/20 0.65
MAPT P10636 7/20 0.64
NPC1 O15118 2/20 0.64
RAB9A P51151 2/20 0.64
MAOB P27338 2/20 0.64
NFKB1 P19838 2/20 0.62
CA1 P00915 1/20 0.62
CA2 P00918 1/20 0.62
CA4 P22748 1/20 0.62
MEN1 O00255 2/20 0.59
KMT2A Q03164 2/20 0.59
HSP90AA1 P07900 1/20 0.59
PTGER3 P43115 3/20 0.58
PTGER2 P43116 3/20 0.58
PTGER1 P34995 2/20 0.58
LMNA P02545 2/20 0.56
L3MBTL1 Q9Y468 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL211297 1.00 HDAC1 (0.65) HDAC1HDAC8HDAC6GSRMAPT
SCHEMBL12852987 1.00 HDAC1 (0.65) HDAC1HDAC8HDAC6GSRMAPT
SCHEMBL322878 1.00 HDAC1 (0.65) HDAC1HDAC8HDAC6GSRMAPT
Hydrochloric Acid SCHEMBL11754749 0.98 HDAC1 (0.62) HDAC1HDAC8HDAC6GSRMAPT
SCHEMBL11462614 0.98 HDAC1 (0.62) HDAC1HDAC8HDAC6GSRMAPT
Juarezic Acid SCHEMBL7524344 0.87 HDAC1 (0.55) HDAC1HDAC8HDAC6GSRMAPT
SCHEMBL1399154 0.86 HDAC1 (0.54) HDAC1HDAC8HDAC6GSRMAPT
SCHEMBL1233338 0.86 HDAC1 (0.54) HDAC1HDAC8HDAC6GSRMAPT
SCHEMBL2744242 0.85 GSR (0.79) HDAC1HDAC8HDAC6GSRMAPT
SCHEMBL22596712 0.85 HDAC1 (0.67) HDAC1HDAC8HDAC6GSRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117430125-B Preparation method and application of manganese doped mesoporous structure-containing acidic Beta zeolite molecular sieve 常州大学 2025-03-21 CN claimed
CN-117430125-A Preparation method and application of manganese doped mesoporous structure-containing acidic Beta zeolite molecular sieve 常州大学 2024-01-23 CN claimed
CN-116003710-A Polyacrylic polymer modified substrate, preparation method thereof and application thereof in preparation of biochip 中国海洋大学 2023-04-25 CN claimed
CN-116396257-B Dihydrocoumarin Process for the preparation of compounds 河南中烟工业有限责任公司 2025-06-10 CN disclosed
CN-116003710-B Polyacrylic polymer modified substrate, preparation method thereof and application thereof in preparation of biochip 中国海洋大学 2025-04-08 CN disclosed
CN-117430125-B Preparation method and application of manganese doped mesoporous structure-containing acidic Beta zeolite molecular sieve 常州大学 2025-03-21 CN disclosed
CN-114058369-B Fluorescent probe based on styryl oxazolone compound and biological application thereof 中国科学院上海药物研究所 2024-07-02 CN disclosed
CN-117430125-A Preparation method and application of manganese doped mesoporous structure-containing acidic Beta zeolite molecular sieve 常州大学 2024-01-23 CN disclosed
CN-116234798-A Sulfamate derivative compounds for the treatment or alleviation of psychotic disorders 生物药品解决方案有限公司 2023-06-06 CN disclosed
CN-116003710-A Polyacrylic polymer modified substrate, preparation method thereof and application thereof in preparation of biochip 中国海洋大学 2023-04-25 CN disclosed
CN-114058369-A Fluorescent probe based on styrene oxazolone compound and biological application thereof 中国科学院上海药物研究所 2022-02-18 CN disclosed