Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 20/20 | 1.00 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 1.00 |
| ▸ | CYP2C8 | P10632 | 1/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 1/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 1/20 | 1.00 |
| ▸ | ADRA2B | P18089 | 1/20 | 1.00 |
| ▸ | HTR2C | P28335 | 1/20 | 1.00 |
| ▸ | P2RX3 | P56373 | 1/20 | 1.00 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 1.00 |
| ▸ | P2RX7 | Q99572 | 1/20 | 1.00 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.64 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bay-1797 SCHEMBL31722451 | 1.00 | P2RX4 (1.00) | P2RX4TMEM97CYP2C8CYP2D6CYP2C9 | |
| Bay-1797 SCHEMBL18301630 | 1.00 | P2RX4 (1.00) | P2RX4TMEM97CYP2C8CYP2D6CYP2C9 | |
| Bay-1797 SCHEMBL31290109 | 1.00 | P2RX4 (1.00) | P2RX4TMEM97CYP2C8CYP2D6CYP2C9 | |
| SCHEMBL30591438 | 0.95 | P2RX4 (0.90) | P2RX4TMEM97CYP2C8CYP2D6CYP2C9 | |
| SCHEMBL18301740 | 0.95 | P2RX4 (0.90) | P2RX4TMEM97CYP2C8CYP2D6CYP2C9 | |
| SCHEMBL18301693 | 0.94 | P2RX4 (1.00) | P2RX4TMEM97CYP2C8CYP2D6CYP2C9 | |
| SCHEMBL31290148 | 0.94 | P2RX4 (1.00) | P2RX4TMEM97CYP2C8CYP2D6CYP2C9 | |
| SCHEMBL18301784 | 0.92 | P2RX4 (0.89) | P2RX4TMEM97CYP2C8CYP2D6CYP2C9 | |
| SCHEMBL31290019 | 0.92 | P2RX4 (0.89) | P2RX4TMEM97CYP2C8CYP2D6CYP2C9 | |
| SCHEMBL18301774 | 0.91 | P2RX4 (1.00) | P2RX4TMEM97CYP2C8CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025229484-A1 | PURINERGIC P2 RECEPTOR ANTAGONISTS FOR USE IN THE TREATMENT OF CONGENITAL SIDEROBLASTIC ANEMIAS | UNIVERSITÀ DEGLI STUDI DI BARI ALDO MORO (IT) | 2025-11-06 | — | — | WO | disclosed |
| EP-4196122-A1 | IMMUNE MODULATION OF MYELOID DERIVED SUPPRESSIVE CELL FUNCTION FOR CANCER TREATMENT | Surge Therapeutics, Inc. (US) | 2023-06-21 | — | — | EP | disclosed |
| WO-2022040246-A1 | IMMUNE MODULATION OF MYELOID DERIVED SUPPRESSIVE CELL FUNCTION FOR CANCER TREATMENT | STIMIT CORPORATION (US) | 2022-02-24 | — | — | WO | disclosed |