SCHEMBL2939475

SCHEMBL2939475

OCCc1nccc(Cl)c1COC1CCCCO1

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM4C Q9H3R0 1/20 0.38
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.36
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
CCNA2 P20248 1/20 0.35
CDK2 P24941 1/20 0.35
CCNA1 P78396 1/20 0.35
CDK5 Q00535 1/20 0.35
CDK5R1 Q15078 1/20 0.35
ICAM1 P05362 1/20 0.32
SELE P16581 1/20 0.32
CREBBP Q92793 1/20 0.31
P2RX3 P56373 1/20 0.30
ADORA3 P0DMS8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1563273 0.91 MEN1 (0.38) KDM4CMEN1KMT2AL3MBTL1NPC1
SCHEMBL1710285 0.86 MEN1 (0.35) KDM4CMEN1KMT2AL3MBTL1NPC1
SCHEMBL1563149 0.83 KDM4C (0.40) KDM4CMEN1KMT2AL3MBTL1NPC1
SCHEMBL1564816 0.78 CCNA2 (0.38) MEN1KMT2ANPC1RAB9ACCNA2
SCHEMBL1563199 0.78 MEN1 (0.36) KDM4CMEN1KMT2AL3MBTL1NPC1
SCHEMBL1563218 0.78 MEN1 (0.37) KDM4CMEN1KMT2AL3MBTL1NPC1
SCHEMBL1564124 0.78 KDM4C (0.37) KDM4CMEN1KMT2AL3MBTL1NPC1
SCHEMBL1564476 0.76 NPC1 (0.39) KDM4CMEN1KMT2AL3MBTL1NPC1
SCHEMBL25227736 0.75 KDM4C (0.43) KDM4CMEN1KMT2AL3MBTL1NPC1
SCHEMBL31317575 0.75 KDM4C (0.43) KDM4CMEN1KMT2AL3MBTL1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2225003-A2 METHODS AND KITS FOR PERMANENTLY COLORING HAIR USING PERSULFATES, PERBORATES OR PERCARBONATES L'Oréal (FR) 2010-09-08 EP disclosed
EP-2144897-A1 8-OXY-QUINOLINE DERIVATIVES AS BRADYKININ B2 RECEPTOR MODULATORS Jerini AG (DE) 2010-01-20 EP disclosed
WO-2009010883-A2 METHODS AND KITS FOR PERMANENTLY COLORING HAIR L'OREAL (FR) 2009-01-22 WO disclosed
WO-2008116620-A1 8-OXY-QUINOLINE DERIVATIVES AS BRADYKININ B2 RECEPTOR MODULATORS JERINI AG (DE) 2008-10-02 WO disclosed