Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.46 |
| ▸ | FLT3 | P36888 | 6/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.43 |
| ▸ | PIM1 | P11309 | 2/20 | 0.43 |
| ▸ | PRKACA | P17612 | 2/20 | 0.43 |
| ▸ | CLK2 | P49760 | 2/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.43 |
| ▸ | MAP4K2 | Q12851 | 2/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.43 |
| ▸ | PLK4 | O00444 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.43 |
| ▸ | INSR | P06213 | 1/20 | 0.43 |
| ▸ | ROS1 | P08922 | 1/20 | 0.43 |
| ▸ | PHKG2 | P15735 | 1/20 | 0.43 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1013458 | 1.00 | MAPT (0.47) | MAPTMAPK14FLT3MAP4K4PIM1 | |
| SCHEMBL6343666 | 0.84 | KDM4E (0.50) | MAPTMAPK14FLT3MAP4K4PIM1 | |
| SCHEMBL16768793 | 0.81 | MAPK14 (0.49) | MAPTMAPK14FLT3MAP4K4PIM1 | |
| SCHEMBL4077901 | 0.81 | MAPK14 (0.52) | MAPTMAPK14FLT3MAP4K4PIM1 | |
| SCHEMBL12759919 | 0.81 | MAPK14 (0.46) | MAPTMAPK14FLT3MAP4K4PIM1 | |
| SCHEMBL298130 | 0.81 | MAPK14 (0.44) | MAPTMAPK14FLT3MAP4K4PIM1 | |
| SCHEMBL29395908 | 0.80 | KDM4E (0.42) | MAPK14MAPK13MAPK12MAPK11CDK8 | |
| SCHEMBL20627781 | 0.79 | MAPK14 (0.56) | MAPK14MAPK13MAPK12MAPK11JAK2 | |
| SCHEMBL6343068 | 0.79 | CYP1A2 (0.59) | MAPTMAPK14FLT3MAP4K4PIM1 | |
| SCHEMBL2788198 | 0.79 | GRN (0.51) | MAPTMAPK14FLT3MAP4K4PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3999057-A1 | POLYAROMATIC UREA DERIVATIVES AND THEIR USE IN THE TREATMENT OF MUSCLE DISEASES | ANAGENESIS BIOTECHNOLOGIES SAS (FR) | 2022-05-25 | — | — | EP | disclosed |
| CN-114144410-A | Polyarylurea derivatives and their use in the treatment of muscular diseases | 阿纳格纳斯生物技术股份有限公司 | 2022-03-04 | — | — | CN | disclosed |