Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 6/20 | 0.57 |
| ▸ | OXTR | P30559 | 4/20 | 0.57 |
| ▸ | FFAR2 | O15552 | 6/20 | 0.50 |
| ▸ | AVPR2 | P30518 | 3/20 | 0.49 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.45 |
| ▸ | GHSR | Q92847 | 1/20 | 0.42 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.42 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.42 |
| ▸ | CDK4 | P11802 | 1/20 | 0.42 |
| ▸ | CCND1 | P24385 | 1/20 | 0.42 |
| ▸ | EDNRB | P24530 | 1/20 | 0.41 |
| ▸ | EDNRA | P25101 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5481411 | 1.00 | AVPR1A (0.57) | AVPR1AOXTRFFAR2AVPR2SLC6A7 | |
| SCHEMBL6017547 | 1.00 | AVPR1A (0.57) | AVPR1AOXTRFFAR2AVPR2SLC6A7 | |
| SCHEMBL17413589 | 0.87 | AVPR1A (0.56) | AVPR1AOXTRFFAR2AVPR2SLC6A7 | |
| SCHEMBL5481224 | 0.86 | HPGD (0.46) | OXTRFFAR2SLC6A7 | |
| SCHEMBL4428848 | 0.83 | AVPR1A (0.69) | AVPR1AOXTRFFAR2AVPR2SLC6A7 | |
| SCHEMBL4428850 | 0.83 | AVPR1A (0.69) | AVPR1AOXTRFFAR2AVPR2SLC6A7 | |
| SCHEMBL24313450 | 0.83 | AVPR1A (0.79) | AVPR1AOXTRFFAR2AVPR2SLC6A7 | |
| SCHEMBL4416107 | 0.83 | AVPR1A (0.79) | AVPR1AOXTRFFAR2AVPR2SLC6A7 | |
| SCHEMBL5034150 | 0.83 | AVPR1A (0.79) | AVPR1AOXTRFFAR2AVPR2SLC6A7 | |
| SCHEMBL29449382 | 0.83 | AVPR1A (0.79) | AVPR1AOXTRFFAR2AVPR2SLC6A7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4129979-A1 | PYRROLIDINE DERIVATIVES AS OXYTOCIN/VASOPRESSIN V1A RECEPTORS ANTAGONISTS | ObsEva S.A. (CH) | 2023-02-08 | — | — | EP | disclosed |
| CN-110960495-B | Oral formulations of pyrrolidine derivatives | 奥布赛瓦股份公司 | 2022-05-10 | — | — | CN | disclosed |
| EP-3252037-B1 | PROCESS FOR THE PREPARATION OF (3Z,5S)-5-(HYDROXYMETHYL)-1-[(2´-METHYL-1,1´-BIPHENYL-4-YL)CARBONYL)PYRROLIDIN-3-ONE O-METHYLOXIME | ObsEva SA (CH) | 2022-03-09 | — | — | EP | disclosed |
| CN-114105850-A | Crystals useful in methods of treating disorders associated with OT-R activity | 奥布赛瓦股份公司 | 2022-03-01 | — | — | CN | disclosed |
| CN-114105851-A | Crystals useful in methods of treating disorders associated with OT-R activity | 奥布赛瓦股份公司 | 2022-03-01 | — | — | CN | disclosed |