Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.76 |
| ▸ | SLC6A9 | P48067 | 6/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KAT6A | Q92794 | 3/20 | 0.43 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18706602 | 1.00 | GBA1 (0.76) | GBA1SLC6A9ADRB1ALDH1A1TSHR | |
| SCHEMBL16832012 | 1.00 | GBA1 (0.76) | GBA1SLC6A9ADRB1ALDH1A1TSHR | |
| SCHEMBL16831311 | 0.86 | GBA1 (0.68) | GBA1ADRB1ALDH1A1MEN1KMT2A | |
| SCHEMBL31494043 | 0.86 | GBA1 (0.68) | GBA1ADRB1ALDH1A1MEN1KMT2A | |
| SCHEMBL16831398 | 0.86 | GBA1 (0.68) | GBA1ADRB1ALDH1A1MEN1KMT2A | |
| SCHEMBL16831309 | 0.86 | GBA1 (0.68) | GBA1ADRB1ALDH1A1MEN1KMT2A | |
| SCHEMBL22870051 | 0.83 | GBA1 (0.52) | GBA1SLC6A9ALDH1A1KMT2AKAT6A | |
| SCHEMBL15621005 | 0.82 | GBA1 (0.63) | GBA1ALDH1A1MEN1KMT2AATM | |
| SCHEMBL31306016 | 0.81 | GBA1 (0.51) | GBA1ALDH1A1KMT2AATMMAPT | |
| SCHEMBL26625722 | 0.81 | GBA1 (0.51) | GBA1ALDH1A1KMT2AATMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116669744-A | Nrf2 activating compounds | 千寿制药株式会社 | 2023-08-29 | — | — | CN | disclosed |
| WO-2022145459-A1 | NRF2-ACTIVATING COMPOUND | 千寿製薬株式会社 | 2022-07-07 | — | — | WO | disclosed |
| CN-114080389-A | Nrf2 activating compound | 千寿制药株式会社 | 2022-02-22 | — | — | CN | disclosed |