Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 14/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.33 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29396863 | 0.84 | BRAF (0.41) | BRAFADORA3MEN1KMT2A | |
| SCHEMBL2931666 | 0.82 | BRAF (0.56) | BRAF | |
| Hydrochloric Acid SCHEMBL29394699 | 0.81 | BRAF (0.56) | BRAF | |
| SCHEMBL2934765 | 0.78 | BRAF (0.56) | BRAF | |
| SCHEMBL28707068 | 0.77 | BRAF (0.41) | BRAFTHRBMEN1NPC1KMT2A | |
| Hydrochloric Acid SCHEMBL29394203 | 0.76 | BRAF (0.41) | BRAFTHRBMEN1NPC1KMT2A | |
| SCHEMBL29394175 | 0.74 | BRD4 (0.38) | MEN1KMT2A | |
| SCHEMBL1042504 | 0.71 | HPGD (0.48) | ADORA2AMEN1KMT2A | |
| SCHEMBL14705752 | 0.70 | BRAF (0.55) | BRAF | |
| SCHEMBL28700841 | 0.70 | BRAF (0.36) | BRAFMEN1NPC1KMT2AAPOBEC3G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3999057-A1 | POLYAROMATIC UREA DERIVATIVES AND THEIR USE IN THE TREATMENT OF MUSCLE DISEASES | ANAGENESIS BIOTECHNOLOGIES SAS (FR) | 2022-05-25 | — | — | EP | disclosed |
| CN-114144410-A | Polyarylurea derivatives and their use in the treatment of muscular diseases | 阿纳格纳斯生物技术股份有限公司 | 2022-03-04 | — | — | CN | disclosed |