SCHEMBL29397489

CSCC[C@H](NC(=O)[C@@H](N)CCC(N)=O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@H](C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)O)C(C)C

nearest known ligand 0.62

Predicted protein targets (top 3)

	gene	UniProt	supporting neighbours	confidence
▸	BACE1	P56817	19/20	0.62

▸	CTSD	P07339	2/20	0.60

▸	BACE2	Q9Y5Z0	5/20	0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29396146	0.96	BACE1 (0.62)	BACE1CTSDBACE2
SCHEMBL29397483	0.93	BACE1 (0.68)	BACE1CTSDBACE2
SCHEMBL29394515	0.93	BACE1 (0.68)	BACE1CTSDBACE2
SCHEMBL29397926	0.93	BACE1 (0.67)	BACE1CTSDBACE2
SCHEMBL30029172	0.92	BACE1 (0.59)	BACE1CTSDBACE2
SCHEMBL32670624	0.91	BACE1 (0.61)	BACE1
SCHEMBL30175896	0.91	BACE1 (0.68)	BACE1CTSDBACE2
SCHEMBL31261771	0.90	TFPI (0.56)	BACE1CTSDBACE2
SCHEMBL31257037	0.89	BACE1 (0.60)	BACE1CTSDBACE2
SCHEMBL31672188	0.89	BACE1 (0.65)	BACE1BACE2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-4196495-A1	EXENDIN-4 PEPTIDE ANALOGUES	TXP Pharma GmbH (CH)	2023-06-21	—	—	EP	claimed
WO-2022034062-A1	EXENDIN-4 PEPTIDE ANALOGUES	TXP PHARMA AG (CH)	2022-02-17	—	—	WO	claimed
EP-4196495-A1	EXENDIN-4 PEPTIDE ANALOGUES	TXP Pharma GmbH (CH)	2023-06-21	—	—	EP	disclosed
WO-2022034062-A1	EXENDIN-4 PEPTIDE ANALOGUES	TXP PHARMA AG (CH)	2022-02-17	—	—	WO	disclosed