SCHEMBL29398199

SCHEMBL29398199

O=C(CC[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)ON1C(=O)CCC1=O)ON1C(=O)CCC1=O

nearest known ligand 0.46

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ MDM4 O15151 1/20 0.45
▸ TP53 P04637 1/20 0.45
▸ KMT2A Q03164 2/20 0.44
▸ TLR2 O60603 2/20 0.44
▸ CASP3 P42574 2/20 0.43
▸ MDM2 Q00987 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10313728 1.00 MDM4 (0.45) MDM4TP53KMT2ATLR2CASP3
SCHEMBL30338374 1.00 MDM4 (0.45) MDM4TP53KMT2ATLR2CASP3
SCHEMBL12658111 0.96 PTPN1 (0.44) MDM4TP53KMT2ATLR2
SCHEMBL30483321 0.94 TLR2 (0.44) MDM4TP53TLR2CASP3MDM2
SCHEMBL19670752 0.92 KMT2A (0.45) MDM4TP53KMT2ATLR2MDM2
SCHEMBL31591666 0.92 KMT2A (0.48) MDM4TP53KMT2ATLR2CASP3
SCHEMBL29412202 0.91 MDM4 (0.44) MDM4TP53KMT2ATLR2MDM2
SCHEMBL31292141 0.91 MDM4 (0.45) MDM4TP53TLR2CASP3MDM2
SCHEMBL20732314 0.91 MDM4 (0.45) MDM4TP53TLR2CASP3MDM2
SCHEMBL12658043 0.91 MDM2 (0.44) MDM4TP53TLR2MDM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4425181-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE Bertis Inc (KR) 2024-09-04 — — EP disclosed
US-20240011979-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS INC. (KR) 2024-01-11 — — US disclosed
CN-116829949-A Compositions for detecting or measuring analytes 伯蒂斯有限公司 2023-09-29 — — CN disclosed
WO-2023075435-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE 주식회사 베르티스 2023-05-04 — — WO disclosed
US-20220283131-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS CO., LTD. (KR) 2022-09-08 — — US disclosed
WO-2022050529-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE ㈜베르티스 2022-03-10 — — WO disclosed
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