Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 7/20 | 0.39 |
| ▸ | NAMPT | P43490 | 4/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6171681 | 0.79 | IGF1R (0.43) | IGF1RNAMPT | |
| SCHEMBL6171670 | 0.75 | IGF1R (0.38) | IGF1R | |
| SCHEMBL2939826 | 0.74 | IGF1R (0.53) | IGF1REPHX2 | |
| SCHEMBL6173623 | 0.74 | IGF1R (0.38) | IGF1RNAMPT | |
| SCHEMBL2941440 | 0.72 | IGF1R (0.56) | IGF1R | |
| SCHEMBL2938212 | 0.71 | IGF1R (0.40) | IGF1R | |
| SCHEMBL2941481 | 0.70 | IGF1R (0.62) | IGF1RNAMPT | |
| SCHEMBL2942119 | 0.70 | IGF1R (0.58) | IGF1R | |
| SCHEMBL2936682 | 0.69 | IGF1R (0.63) | IGF1R | |
| SCHEMBL2940341 | 0.69 | IGF1R (0.40) | IGF1RNAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1599464-B1 | NOVEL CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | AVENTIS PHARMA SA (FR) | 2010-09-22 | — | — | EP | disclosed |