Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | AHR | P35869 | 2/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 2/20 | 0.39 |
| ▸ | TDO2 | P48775 | 7/20 | 0.39 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22558952 | 1.00 | MEN1 (0.46) | MEN1MAPTKMT2AAHRNR1I2 | |
| SCHEMBL22558943 | 0.91 | MEN1 (0.46) | MEN1MAPTKMT2AAHRNR1I2 | |
| SCHEMBL29396450 | 0.87 | MEN1 (0.43) | MEN1MAPTKMT2AAHRNR1I2 | |
| SCHEMBL22585134 | 0.87 | MEN1 (0.43) | MEN1MAPTKMT2AAHRNR1I2 | |
| SCHEMBL22559042 | 0.87 | MEN1 (0.43) | MEN1MAPTKMT2AAHRNR1I2 | |
| SCHEMBL22558955 | 0.86 | MEN1 (0.44) | MEN1MAPTKMT2AAHRNR1I2 | |
| SCHEMBL29396189 | 0.86 | MEN1 (0.43) | MEN1MAPTKMT2AAHRNR1I2 | |
| SCHEMBL22559029 | 0.86 | MEN1 (0.43) | MEN1MAPTKMT2AAHRNR1I2 | |
| SCHEMBL22558925 | 0.84 | MEN1 (0.42) | MEN1MAPTKMT2AAHRNR1I2 | |
| SCHEMBL22559141 | 0.83 | MEN1 (0.42) | MEN1MAPTKMT2AAHRNR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3956327-A1 | CHIRAL INDOLE COMPOUNDS AND THEIR USE | Ariagen, Inc. (US) | 2022-02-23 | — | — | EP | disclosed |