SCHEMBL29398614

CC[C@H](C)[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N[C@@H](CC(N)=O)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)O)C(=O)O)[C@@H](C)O)C(C)C

nearest known ligand 0.66

Predicted protein targets (top 4)

	gene	UniProt	supporting neighbours	confidence
▸	GLP1R	P43220	20/20	0.66

▸	SCTR	P47872	1/20	0.62

▸	ECE1	P42892	1/20	0.60

▸	MUS81	Q96NY9	1/20	0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30887553	0.99	GLP1R (0.66)	GLP1RSCTRECE1MUS81
SCHEMBL31410870	0.95	GLP1R (0.61)	GLP1RSCTRECE1MUS81
SCHEMBL30168743	0.94	GLP1R (0.63)	GLP1RSCTRECE1MUS81
SCHEMBL30168759	0.94	GLP1R (0.63)	GLP1RSCTRECE1MUS81
SCHEMBL31182730	0.94	GLP1R (0.72)	GLP1RSCTRECE1MUS81
SCHEMBL31410848	0.93	GLP1R (0.62)	GLP1RSCTRECE1MUS81
SCHEMBL30168698	0.93	GLP1R (0.63)	GLP1RSCTRECE1MUS81
SCHEMBL29836187	0.93	GLP1R (0.63)	GLP1RECE1MUS81
SCHEMBL29836537	0.93	GLP1R (0.63)	GLP1RECE1MUS81
SCHEMBL31182816	0.92	GLP1R (0.69)	GLP1RSCTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-1812062-B1	ANTI-ADDL ANTIBODIES AND USES THEREOF	MERCK SHARP & DOHME (US)	2022-03-09	—	—	EP	claimed
EP-1812062-B1	ANTI-ADDL ANTIBODIES AND USES THEREOF	MERCK SHARP & DOHME (US)	2022-03-09	—	—	EP	disclosed