Gamma-Amino-Beta-Hydroxybutyric Acid

Gamma-Amino-Beta-Hydroxybutyric Acid

SCHEMBL2940090

NC[C@H](O)CC(=O)O

nearest known ligand 0.00

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⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 206 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110551052-A Preparation method of (R) -4-hydroxy-2-oxo-1-pyrrolidine acetate CHONGQING RUNZE PHARMACEUTICAL 2019-12-10 CN claimed
CN-110551053-A preparation method of dextro-oxypyr-mepyramine CHONGQING RUNZE PHARMACEUTICAL 2019-12-10 CN claimed
CN-109251157-A (R)-Esomeprazole preparation method 重庆润泽医药有限公司 2019-01-22 CN claimed
US-7816119-B2 Chemoenzymatic process for the stereoselective preparation of (R)-γ-amino-β-hydroxybutyric acid or (R)-carnitine from 3,4-dihydroxybutanenitrile COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2010-10-19 US claimed
EP-1833977-B1 ENANTIOCONVERGENT CHEMOENZYMATIC SYNTHESIS OF (R)- GAMMA-AMINO-BETA-HYDROXYBUTYRIC ACID ((R) - GABOB) COUNCIL SCIENT IND RES (IN) 2009-04-29 EP claimed
US-7374926-B2 Enantioconvergent chemoenzymatic synthesis of (R)-γ-amino-β-hydroxybutyric acid ((R)-GABOB) COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2008-05-20 US claimed
EP-1100768-B1 PROCESS FOR THE PREPARATION OF R-(-)-CARNITINE SIGMA TAU IND FARMACEUTI (IT) 2002-10-02 EP claimed
US-6316667-B2 DECYCLIZATION OF 3-HYDROXY-4-BUTYROLACTONE TO ALKYL 4-HALOGEN-3-HYDROXYBUTYRATE BY REACTION WITH ALCOHOL; CYANATION, AMIDATION, CYCLIZATION TO OXAZOLIDONE; HYDROLYSIS, METHYLATION, QUATERNIZATION SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) 2001-11-13 US claimed
US-20010031892-A1 Process for the preparation of R-(-)-carnitine SIGMA-TAU INDUSTRIE FARMACUETICHE RIUNITE S.P.A. (IT) 2001-10-18 US claimed
EP-1100768-A2 PROCESS FOR THE PREPARATION OF R-(-)-CARNITINE Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) 2001-05-23 EP claimed
WO-2000006532-A2 PROCESS FOR THE PREPARATION OF R-(-)-CARNITINE SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) 2000-02-10 WO claimed
US-4886908-A Method of preparing (R)-4-amino-3-hydroxybutyric acid DEGUSSA AKTIENGESELLSCHAFT (DE) 1989-12-12 US claimed
EP-0165226-B1 4-AMINO-BUTANOIC-ACID DERIVATIVES, PREPARATION AND USE SANOFI (FR) 1989-03-15 EP claimed
EP-0169614-B1 PROCESS FOR THE PREPARATION OF L-CARNITINE SCLAVO S.p.A. (IT) 1988-11-30 EP claimed
EP-0169614-A2 Process for the preparation of L-carnitine SCLAVO S.p.A. (IT) 1986-01-29 EP claimed
JP-63316759-A None JP disclosed
JP-63316758-A None JP disclosed
US-4461906-A IMPROVING INTELLECTUAL CAPACITY HOFFMANN-LA ROCHE INC. (US) 1984-07-24 US disclosed
US-4124594-A REACTING AMINO-HYDROXYBUTYRIC ACID WITH A SILYLATING AGENT FOLLOWED BY REACTION WITH A HALOGENATED ESTER, CYCLIZATION I.S.F. SPA (IT) 1978-11-07 US disclosed
JP-S52133933-A 4-AMINO-3-HYDROXYBUTANOIC ACID ANILIDE, ITS ACIDIC SALTS AND PREPARATION THEREOF ONO PHARMACEUT CO LTD 1977-11-09 JP disclosed