SCHEMBL29401511

SCHEMBL29401511

CC(C)(C)OC(=O)Nc1ccc(C[C@@H](NC(=O)OCC2c3ccccc3-c3ccccc32)C(=O)O)cc1

nearest known ligand 0.62

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MDM2 Q00987 1/20 0.62
PTPN1 P18031 2/20 0.51
MDM4 O15151 2/20 0.49
TP53 P04637 2/20 0.49
ACE P12821 1/20 0.49
ITGB3 P05106 1/20 0.49
ITGB1 P05556 1/20 0.49
ITGAV P06756 1/20 0.49
ITGA2B P08514 1/20 0.49
ITGB5 P18084 1/20 0.49
HDAC8 Q9BY41 1/20 0.46
CASP3 P42574 1/20 0.46
FPR2 P25090 1/20 0.45
EPHX2 P34913 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2307978 1.00 MDM2 (0.62) MDM2PTPN1MDM4TP53ACE
SCHEMBL14039181 1.00 MDM2 (0.62) MDM2PTPN1MDM4TP53ACE
SCHEMBL3728072 1.00 MDM2 (0.62) MDM2PTPN1MDM4TP53ACE
SCHEMBL29445607 1.00 MDM2 (0.62) MDM2PTPN1MDM4TP53ACE
SCHEMBL31370376 0.97 MDM2 (0.64) MDM2PTPN1MDM4TP53ACE
SCHEMBL503172 0.96 MDM2 (0.58) MDM2PTPN1MDM4TP53ACE
SCHEMBL2249260 0.96 MDM2 (0.58) MDM2PTPN1MDM4TP53ACE
SCHEMBL371161 0.96 MDM2 (0.58) MDM2PTPN1MDM4TP53ACE
SCHEMBL25357720 0.91 MDM2 (0.65) MDM2MDM4TP53CASP3EPHX2
SCHEMBL25358626 0.91 MDM2 (0.65) MDM2MDM4TP53CASP3EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4637845-A1 RADIOLABELED PSMA LIGAND COMPOUNDS AND PRECURSORS THEREOF Technische Universität München (DE) 2025-10-29 EP disclosed
EP-4425181-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE Bertis Inc (KR) 2024-09-04 EP disclosed
WO-2024133174-A1 RADIOLABELED PSMA LIGAND COMPOUNDS AND PRECURSORS THEREOF Technische Universität München (DE) 2024-06-27 WO disclosed
EP-4389156-A1 RADIOLABELED PSMA LIGAND COMPOUNDS AND PRECURSORS THEREOF Technische Universität München (DE) 2024-06-26 EP disclosed
US-20240011979-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS INC. (KR) 2024-01-11 US disclosed
WO-2023075435-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE 주식회사 베르티스 2023-05-04 WO disclosed
US-20220283131-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS CO., LTD. (KR) 2022-09-08 US disclosed
WO-2022050529-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE ㈜베르티스 2022-03-10 WO disclosed