Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 20/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3726795 | 0.94 | IGF1R (0.60) | IGF1R | |
| SCHEMBL1130587 | 0.80 | IGF1R (1.00) | IGF1R | |
| SCHEMBL2943071 | 0.79 | IGF1R (0.80) | IGF1R | |
| SCHEMBL2931813 | 0.79 | IGF1R (0.74) | IGF1R | |
| SCHEMBL2939981 | 0.79 | IGF1R (1.00) | IGF1R | |
| SCHEMBL2997912 | 0.78 | IGF1R (0.59) | IGF1R | |
| SCHEMBL13039149 | 0.78 | IGF1R (0.69) | IGF1R | |
| SCHEMBL2934949 | 0.77 | IGF1R (0.60) | IGF1R | |
| SCHEMBL2939123 | 0.76 | IGF1R (0.67) | IGF1R | |
| SCHEMBL13039168 | 0.76 | IGF1R (0.63) | IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1599464-B1 | NOVEL CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | AVENTIS PHARMA SA (FR) | 2010-09-22 | — | — | EP | disclosed |