Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 6/20 | 0.51 |
| ▸ | CRBN | Q96SW2 | 6/20 | 0.51 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.42 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 6/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.40 |
| ▸ | HTR4 | Q13639 | 3/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24269178 | 1.00 | DDB1 (0.51) | DDB1CRBNCACNA1GCACNA1HOPRL1 | |
| SCHEMBL24269308 | 0.89 | DDB1 (0.51) | DDB1CRBNOPRL1OPRM1OPRK1 | |
| SCHEMBL31586188 | 0.87 | DDB1 (0.60) | DDB1CRBNCACNA1GCACNA1HOPRM1 | |
| SCHEMBL24269179 | 0.87 | DDB1 (0.48) | DDB1CRBNOPRL1OPRM1HTR4 | |
| SCHEMBL31586555 | 0.83 | DDB1 (0.58) | DDB1CRBNCACNA1GCACNA1HOPRM1 | |
| SCHEMBL22512101 | 0.83 | DDB1 (0.58) | DDB1CRBNCACNA1GCACNA1HOPRM1 | |
| SCHEMBL22511713 | 0.83 | DDB1 (0.58) | DDB1CRBNCACNA1GCACNA1HOPRM1 | |
| SCHEMBL24269127 | 0.80 | CRBN (0.60) | DDB1CRBNOPRL1OPRM1OPRK1 | |
| SCHEMBL24269422 | 0.79 | CRBN (0.59) | DDB1CRBNOPRM1 | |
| SCHEMBL29399917 | 0.79 | CRBN (0.59) | DDB1CRBNOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116507333-B | Cyclic AMP response element binding protein (CBP) and/or 300KDA adenovirus E1A binding protein (P300) degrading compounds and methods of use | 上海睿跃生物科技有限公司 | 2025-05-09 | — | — | CN | disclosed |
| CN-116507333-A | Cyclic AMP response element binding protein (CBP) and/or 300KDA adenovirus E1A binding protein (P300) degrading compounds and methods of use | 上海睿跃生物科技有限公司 | 2023-07-28 | — | — | CN | disclosed |
| WO-2022042707-A1 | CYCLIC-AMP RESPONSE ELEMENT BINDING PROTEIN (CBP) AND/OR ADENOVIRAL E1A BINDING PROTEIN OF 300 KDA (P300) DEGRADATION COMPOUNDS AND METHODS OF USE | CULLGEN (SHANGHAI) , INC. (CN) | 2022-03-03 | — | — | WO | disclosed |