SCHEMBL29403240

SCHEMBL29403240

CCCCCCCCCC[Si](C)(C)CCCCCCCCCC[Si](Cl)(Cl)Cl

nearest known ligand 0.40

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.40
THRB P10828 1/20 0.40
ALDH1A1 P00352 3/20 0.38
DNM1 Q05193 7/20 0.32
LMNA P02545 2/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
HSD17B10 Q99714 1/20 0.32
SLC22A1 O15245 1/20 0.32
EPHX1 P07099 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28148404 0.90 TSHR (0.44) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL23898213 0.90 TSHR (0.44) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL523405 0.89 TSHR (0.50) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL132734 0.89 TSHR (0.50) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL79778 0.89 TSHR (0.50) TSHRTHRBALDH1A1DNM1LMNA
Octane SCHEMBL5665639 0.89 TSHR (0.50) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL367117 0.89 TSHR (0.50) TSHRTHRBALDH1A1DNM1LMNA
Octane SCHEMBL3857273 0.89 TSHR (0.50) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL185494 0.89 TSHR (0.50) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL6754242 0.89 TSHR (0.50) TSHRTHRBALDH1A1DNM1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230185118-A1 OPTICAL DEVICE AND OPTICAL DETECTION SYSTEM PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO., LTD. (JP) 2023-06-15 US disclosed
US-20220365403-A1 OPTICAL DEVICE, OPTICAL DETECTION SYSTEM, AND OPTICAL FIBER PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO., LTD. (JP) 2022-11-17 US disclosed
WO-2022044938-A1 OPTICAL DEVICE AND OPTICAL DETECTION SYSTEM パナソニックIPマネジメント株式会社 2022-03-03 WO disclosed