SCHEMBL2940467

SCHEMBL2940467

COC(=O)C1(CCC(C)C)CCCC1

nearest known ligand 0.57

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 1/20 0.57
CYP4A11 Q02928 1/20 0.57
NPSR1 Q6W5P4 1/20 0.40
CETP P11597 8/20 0.40
MME P08473 2/20 0.37
P2RX7 Q99572 1/20 0.32
HSD11B1 P28845 1/20 0.32
CYP2D6 P10635 1/20 0.32
MAPT P10636 1/20 0.32
LTA4H P09960 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6798315 0.88 CYP4F2 (0.66) CYP4F2CYP4A11NPSR1CETPMME
SCHEMBL9266989 0.84 CYP4F2 (0.56) CYP4F2CYP4A11NPSR1CETPMME
SCHEMBL11919608 0.79 MAPK1 (0.40) CYP4F2CYP4A11MAPT
SCHEMBL10542184 0.78 CETP (0.39) CYP4F2CYP4A11CETPMME
SCHEMBL22086922 0.78 CYP2C19 (0.37) CYP4F2CYP4A11CETP
SCHEMBL8278881 0.77 CYP4F2 (0.71) CYP4F2CYP4A11NPSR1CETPMME
SCHEMBL6627868 0.77 CYP4F2 (0.61) CYP4F2CYP4A11NPSR1MMEP2RX7
SCHEMBL6629252 0.77 CYP4F2 (0.61) CYP4F2CYP4A11NPSR1MMEP2RX7
SCHEMBL13715140 0.77 CYP4F2 (0.47) CYP4F2CYP4A11NPSR1MMEP2RX7
SCHEMBL6385927 0.77 CETP (0.39) CYP4F2CYP4A11CETPMMEHSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2139354-A2 ORGANIC COMPOUNDS Givaudan SA (CH) 2010-01-06 EP disclosed
WO-2008116339-A2 ORGANIC COMPOUNDS GIVAUDAN SA (CH) 2008-10-02 WO disclosed