Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | KLK7 | P49862 | 6/20 | 0.34 |
| ▸ | KLK5 | Q9Y337 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.32 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27084526 | 0.92 | KLK7 (0.36) | ATMCHRM2CHRM1CHRM3ALDH1A1 | |
| SCHEMBL29405280 | 0.81 | CHRM2 (0.35) | CHRM2CHRM1CHRM3ALDH1A1KMT2A | |
| SCHEMBL19420020 | 0.79 | CHRM2 (0.46) | CHRM2CHRM1CHRM3USP2SMN1; SMN2 | |
| SCHEMBL22096750 | 0.79 | CHRM2 (0.46) | CHRM2CHRM1CHRM3USP2SMN1; SMN2 | |
| SCHEMBL23186706 | 0.76 | CHRM2 (0.44) | CHRM2CHRM1CHRM3GLAUSP2 | |
| SCHEMBL29222219 | 0.76 | CHRM2 (0.44) | CHRM2CHRM1CHRM3GLAUSP2 | |
| SCHEMBL26198255 | 0.76 | CHRM2 (0.44) | CHRM2CHRM1CHRM3GLAUSP2 | |
| SCHEMBL22990239 | 0.76 | CHRM2 (0.44) | CHRM2CHRM1CHRM3GLAUSP2 | |
| SCHEMBL18593025 | 0.76 | CHRM2 (0.44) | CHRM2CHRM1CHRM3GLAUSP2 | |
| SCHEMBL3738817 | 0.75 | CHRM2 (0.39) | CHRM2CHRM1CHRM3GLAUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4199905-A1 | METHODS OF NEUROPROTECTION AND USES THEREOF | Oculotherapy, LLC (US) | 2023-06-28 | — | — | EP | disclosed |
| WO-2023028490-A1 | METHODS OF TREATING PAIN AND USES THEREOF | OCULOTHERAPY, LLC (US) | 2023-03-02 | — | — | WO | disclosed |
| WO-2022040622-A1 | METHODS OF NEUROPROTECTION AND USES THEREOF | OCULOTHERAPY, LLC (US) | 2022-02-24 | — | — | WO | disclosed |