Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.55 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.54 |
| ▸ | ABHD6 | Q9BV23 | 6/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.44 |
| ▸ | UCHL1 | P09936 | 2/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19642882 | 1.00 | ESR2 (0.55) | ESR2NR1H2ABHD6MAPK1MKNK1 | |
| SCHEMBL22993468 | 0.90 | ESR2 (0.55) | ESR2NR1H2ABHD6MAPK1MKNK1 | |
| SCHEMBL29391872 | 0.90 | ESR2 (0.55) | ESR2NR1H2ABHD6MAPK1MKNK1 | |
| SCHEMBL29697653 | 0.90 | ESR2 (0.55) | ESR2NR1H2ABHD6MAPK1MKNK1 | |
| SCHEMBL31159106 | 0.88 | HDAC1 (0.46) | ESR2NR1H2ABHD6MAPK1MKNK1 | |
| SCHEMBL19948765 | 0.85 | ESR2 (0.55) | ESR2NR1H2ABHD6MAPK1MKNK1 | |
| SCHEMBL4165540 | 0.85 | NR1H2 (0.60) | ESR2NR1H2ABHD6MAPK1UCHL1 | |
| SCHEMBL31067476 | 0.85 | NR1H2 (0.60) | ESR2NR1H2ABHD6MAPK1UCHL1 | |
| SCHEMBL29446113 | 0.85 | ESR2 (0.55) | ESR2NR1H2ABHD6MAPK1MKNK1 | |
| SCHEMBL15503058 | 0.84 | ESR2 (0.52) | ESR2NR1H2ABHD6MAPK1MKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114206852-A | Plasma kallikrein inhibitors | 卡尔维斯塔制药有限公司 | 2022-03-18 | — | — | CN | disclosed |