Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.76 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.76 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.76 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.76 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.76 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.76 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.76 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.76 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.76 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL229510 | 1.00 | HDAC6 (0.76) | HDAC6HDAC1HDAC3HDAC4HDAC2 | |
| Hydrochloric Acid SCHEMBL2781680 | 0.99 | HDAC6 (0.74) | HDAC6HDAC1HDAC3HDAC4HDAC2 | |
| SCHEMBL12973509 | 0.96 | HDAC6 (0.71) | HDAC6HDAC1HDAC3HDAC4HDAC2 | |
| SCHEMBL16866953 | 0.96 | HDAC6 (0.73) | HDAC6HDAC1HDAC3HDAC4HDAC2 | |
| SCHEMBL16866946 | 0.94 | HDAC6 (0.69) | HDAC6HDAC1HDAC3HDAC4HDAC2 | |
| SCHEMBL14823504 | 0.92 | HDAC6 (0.73) | HDAC6HDAC1HDAC3HDAC4HDAC2 | |
| SCHEMBL16754938 | 0.92 | HDAC6 (0.64) | HDAC6HDAC1HDAC3HDAC4HDAC2 | |
| SCHEMBL15690680 | 0.91 | HDAC6 (0.72) | HDAC6HDAC1HDAC3HDAC4HDAC2 | |
| SCHEMBL31688425 | 0.91 | HDAC6 (0.62) | HDAC6HDAC1HDAC3HDAC4HDAC2 | |
| SCHEMBL365881 | 0.91 | HDAC6 (0.62) | HDAC6HDAC1HDAC3HDAC4HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109422695-B | Preparation method of bendamustine hydrochloride crude product | 扬子江药业集团有限公司 | 2022-03-18 | — | — | CN | claimed |
| EP-3836921-B1 | LIQUID BENDAMUSTINE PHARMACEUTICAL COMPOSITIONS | HOSPIRA AUSTRALIA PTY LTD (AU) | 2025-10-08 | — | — | EP | disclosed |
| US-20250295636-A1 | METHOD FOR PREPARING 4-[5-[BIS(2-CHLOROETHYL)AMINO]-1-METHYL-1H-BENZO[D]IMIDAZOL-2-YL]BUTYRIC ACID ALKYL ESTERS AND FORMYLATED DERIVATIVES | HERAEUS PRECIOUS METALS GMBH & CO. KG (DE) | 2025-09-25 | — | — | US | disclosed |
| US-12246007-B2 | Liquid bendamustine pharmaceutical compositions | HOSPIRA AUSTRALIA PTY LTD (AU) | 2025-03-11 | — | — | US | disclosed |
| CN-119095829-A | Process for preparing alkyl 4- [5- [ bis (2-chloroethyl) amino ] -1-methyl-1H-benzo [ d ] imidazol-2-yl ] butanoates and formylated derivatives | 贺利氏贵金属有限两合公司 | 2024-12-06 | — | — | CN | disclosed |
| CN-109422695-B | Preparation method of bendamustine hydrochloride crude product | 扬子江药业集团有限公司 | 2022-03-18 | — | — | CN | disclosed |
| CN-109422695-B | Preparation method of bendamustine hydrochloride crude product | 扬子江药业集团有限公司 | 2022-03-18 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12246007-B2 | Liquid bendamustine pharmaceutical compositions | JAK2, SLCO4C1, FGFR3 | HDAC6 673/4885HDAC1 2962/4885HDAC3 2873/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.