SCHEMBL29406581

SCHEMBL29406581

CCP(=O)(CC)c1ccc(-n2ccn(-c3c(-c4cc(C)c(F)c(C)c4)nn4c3C(C)N(C(=O)c3cc5cc(C6CCOCC6)ccc5n3C3(c5noc(=O)[nH]5)CC3)CC4)c2=O)cc1NC

nearest known ligand 0.52

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 20/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24277008 1.00 GLP1R (0.52) GLP1R
SCHEMBL29405687 0.94 GLP1R (0.60) GLP1R
SCHEMBL24276782 0.94 GLP1R (0.60) GLP1R
SCHEMBL24276754 0.94 GLP1R (0.60) GLP1R
SCHEMBL24276952 0.92 GLP1R (0.46) GLP1R
SCHEMBL29406888 0.90 GLP1R (0.54) GLP1R
SCHEMBL26185737 0.90 GLP1R (0.54) GLP1R
SCHEMBL24276750 0.90 GLP1R (0.54) GLP1R
SCHEMBL24277198 0.90 GLP1R (0.54) GLP1R
SCHEMBL24277746 0.89 GLP1R (0.62) GLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4211139-A1 HETEROCYCLIC GLP-1 AGONISTS Gasherbrum Bio, Inc. (US) 2023-07-19 — — EP disclosed
CN-116368140-A Heterocyclic GLP-1 agonists 加舒布鲁姆生物公司 2023-06-30 — — CN disclosed
WO-2022052958-A1 HETEROCYCLIC GLP-1 AGONISTS GASHERBRUM BIO, INC. (US) 2022-03-17 — — WO disclosed
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