Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 20/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2951264 | 0.89 | EPHX2 (0.38) | — | |
| SCHEMBL2940452 | 0.84 | BDKRB1 (0.50) | BDKRB1 | |
| SCHEMBL2940684 | 0.83 | BDKRB1 (0.57) | BDKRB1 | |
| SCHEMBL3130675 | 0.83 | BDKRB1 (0.50) | BDKRB1 | |
| SCHEMBL2951261 | 0.72 | BDKRB1 (0.41) | BDKRB1 | |
| SCHEMBL2951268 | 0.71 | ALOX5AP (0.39) | BDKRB1 | |
| SCHEMBL23157049 | 0.70 | KMT2A (0.52) | — | |
| SCHEMBL2949317 | 0.69 | KMT2A (0.51) | — | |
| SCHEMBL3130684 | 0.66 | BDKRB1 (0.66) | BDKRB1 | |
| SCHEMBL2940450 | 0.65 | BDKRB1 (0.68) | BDKRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2396301-A2 | SMALL MOLECULE BRADYKININ B1 RECEPTOR ANTAGONISTS | Jerini AG (DE) | 2011-12-21 | — | — | EP | disclosed |
| WO-2010091876-A2 | SMALL MOLECULE BRADYKININ B1 RECEPTOR ANTAGONISTS | JERINI AG (DE) | 2010-08-19 | — | — | WO | disclosed |