⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butane SCHEMBL10937059 | 0.93 | TSHR (0.39) | — | |
| SCHEMBL2940797 | 0.82 | TSHR (0.46) | — | |
| SCHEMBL3618711 | 0.76 | GAA (0.48) | — | |
| SCHEMBL28170549 | 0.75 | — | — | |
| SCHEMBL14848929 | 0.75 | TSHR (0.39) | — | |
| SCHEMBL15166422 | 0.75 | CYP2D6 (0.32) | — | |
| SCHEMBL3360711 | 0.74 | — | — | |
| SCHEMBL6376208 | 0.73 | — | — | |
| Butane SCHEMBL5481709 | 0.73 | GAA (0.44) | — | |
| SCHEMBL28715254 | 0.72 | TSHR (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111826105-B | Packaging adhesive for LED and use method and application thereof | 北京康美特科技股份有限公司 | 2022-04-15 | — | — | CN | claimed |
| CN-111826105-A | Packaging adhesive for LED and use method and application thereof | 北京康美特科技股份有限公司 | 2020-10-27 | — | — | CN | claimed |
| WO-2024017201-A1 | CBL-B INHIBITORS AND METHODS OF USES THEREOF | INSILICO MEDICINE IP LIMITED (CN) | 2024-01-25 | — | — | WO | disclosed |
| CN-111826105-B | Packaging adhesive for LED and use method and application thereof | 北京康美特科技股份有限公司 | 2022-04-15 | — | — | CN | disclosed |
| CN-113968786-A | Process for preparing two methyl-substituted 2-oxo-3-cyclopentene-1-carboxylate compounds and dicarboxylate compounds for preparation | 信越化学工业株式会社 | 2022-01-25 | — | — | CN | disclosed |
| CN-111826105-A | Packaging adhesive for LED and use method and application thereof | 北京康美特科技股份有限公司 | 2020-10-27 | — | — | CN | disclosed |
| CN-105392777-B | Biaryl derivatives as GPR120 agonists | 株式会社LG化学 | 2020-09-22 | — | — | CN | disclosed |
| CN-105189516-B | Oxabicyclo [2.2.2] acid GPR120 modulators | 百时美施贵宝公司 | 2017-08-15 | — | — | CN | disclosed |
| CN-105392777-A | Biaryl derivatives as GRP120 agonists | LG LIFE SCIENCES LTD | 2016-03-09 | — | — | CN | disclosed |
| CN-105189516-A | Oxabicyclo [2.2.2] acid gpr120 modulators | BRISTOL MYERS SQUIBB CO | 2015-12-23 | — | — | CN | disclosed |
| CN-102746300-A | 8-phenyl-7,8-dihydropyridines[2,3-d]pyrimidine-7-ketone and uses as medicament | GLAXO GROUP LTD | 2012-10-24 | — | — | CN | disclosed |
| WO-2002059124-A2 | SUBSTITUTED PYRROLOQUINOLINES AND PYRIDOQUINOLINES AS SEROTONIN AGONISTS AND ANTAGONISTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2002-08-01 | — | — | WO | disclosed |
| CN-1335834-A | Aromatic heterocyclic compounds having HIV integrase inhibitory activity | SHIONOGI & CO (JP) | 2002-02-13 | — | — | CN | disclosed |
| EP-0934265-A1 | AMIDINOPHENYL-PYRROLIDINES, -PYRROLINES, AND -ISOXAZOLIDINES AND DERIVATIVES THEREOF | Du Pont Pharmaceuticals Company (US) | 1999-08-11 | — | — | EP | disclosed |
| CN-1187191-A | Triazole antifungal agents | SANKYO CO (JP) | 1998-07-08 | — | — | CN | disclosed |
| WO-1998006694-A1 | AMIDINOPHENYL-PYRROLIDINES, -PYRROLINES, AND -ISOXAZOLIDINES AND DERIVATIVES THEREOF | DU PONT PHARMACEUTICALS COMPANY (US) | 1998-02-19 | — | — | WO | disclosed |
| CN-1106003-A | Inhibitors of microsomal triglyceride transfer protein and method | BRISTOL MYERS SQIUBB COMPANY (US) | 1995-08-02 | — | — | CN | disclosed |
| CN-1099380-A | Alicyclic phospholipase A2 inhibitors | BRISTOL MYERS SQUIBB CO (US) | 1995-03-01 | — | — | CN | disclosed |
| US-5177063-A | AVERMECTIN COMPOUNDS WITH A 6,5-SPIROKETAL RING SYSTEM | MERCK & CO., INC. (US) | 1993-01-05 | — | — | US | disclosed |
| EP-0503885-A1 | Avermectin compounds with a 6,5-spiroketal ring system | MERCK & CO. INC. (US) | 1992-09-16 | — | — | EP | disclosed |