Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 3/20 | 0.41 |
| ▸ | PDE4A | P27815 | 2/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.41 |
| ▸ | BACE1 | P56817 | 2/20 | 0.37 |
| ▸ | IKBKB | O14920 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | DHFR | P00374 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.34 |
| ▸ | TUBB | P07437 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22658141 | 1.00 | PDE4B (0.41) | PDE4BPDE4APDE4CPDE4DBACE1 | |
| SCHEMBL22678869 | 0.83 | PDE4B (0.42) | PDE4BPDE4APDE4CPDE4DBACE1 | |
| SCHEMBL22678870 | 0.82 | PDE4B (0.41) | PDE4BPDE4APDE4CPDE4DBACE1 | |
| SCHEMBL22658124 | 0.82 | PDE4B (0.41) | PDE4BPDE4APDE4CPDE4DTUBB4A | |
| SCHEMBL29113865 | 0.82 | PDE4B (0.51) | PDE4BPDE4APDE4CPDE4DBACE1 | |
| SCHEMBL29408241 | 0.81 | PDE4B (0.38) | PDE4BPDE4APDE4CPDE4DBACE1 | |
| SCHEMBL22658167 | 0.81 | PDE4B (0.38) | PDE4BPDE4APDE4CPDE4DBACE1 | |
| SCHEMBL29795424 | 0.76 | DPP4 (0.41) | PDE4BPDE4APDE4CPDE4DBACE1 | |
| SCHEMBL28064439 | 0.76 | FYN (0.50) | PDE4BPDE4APDE4CPDE4DFYN | |
| SCHEMBL27398014 | 0.76 | PTGDR2 (0.43) | BACE1PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114127049-A | ACSS2 inhibitors and methods of use thereof | 美特波米德有限公司 | 2022-03-01 | — | — | CN | disclosed |