Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM6B | O15054 | 6/20 | 1.00 |
| ▸ | KDM6A | O15550 | 5/20 | 1.00 |
| ▸ | KDM5B | Q9UGL1 | 4/20 | 1.00 |
| ▸ | KDM2B | Q8NHM5 | 4/20 | 1.00 |
| ▸ | KDM5C | P41229 | 3/20 | 1.00 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 1.00 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 1.00 |
| ▸ | KDM4A | O75164 | 2/20 | 1.00 |
| ▸ | KDM4B | O94953 | 2/20 | 1.00 |
| ▸ | KDM3A | Q9Y4C1 | 2/20 | 1.00 |
| ▸ | KDM3B | Q7LBC6 | 1/20 | 1.00 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 1.00 |
| ▸ | KDM5A | P29375 | 3/20 | 0.77 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.77 |
| ▸ | MAOB | P27338 | 2/20 | 0.77 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.77 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.77 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.77 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14931829 | 1.00 | KDM6B (1.00) | KDM6BKDM6AKDM5BKDM2BKDM5C | |
| SCHEMBL29373519 | 1.00 | KDM6B (1.00) | KDM6BKDM6AKDM5BKDM2BKDM5C | |
| Hydrochloric Acid SCHEMBL29352956 | 0.99 | KDM6B (0.98) | KDM6BKDM6AKDM5BKDM2BKDM5C | |
| Hydrochloric Acid SCHEMBL30127895 | 0.99 | KDM6B (0.98) | KDM6BKDM6AKDM5BKDM2BKDM5C | |
| SCHEMBL18159121 | 0.92 | KDM6B (0.85) | KDM6BKDM6AKDM5BKDM2BKDM5C | |
| SCHEMBL22462414 | 0.90 | KDM6B (0.81) | KDM6BKDM6AKDM5BKDM2BKDM5C | |
| SCHEMBL10157593 | 0.89 | KDM6A (0.81) | KDM6BKDM6AKDM5BKDM2BKDM5C | |
| SCHEMBL10156416 | 0.89 | KDM6A (0.81) | KDM6BKDM6AKDM5BKDM2BKDM5C | |
| SCHEMBL17899150 | 0.88 | KDM6B (0.84) | KDM6BKDM6AKDM5BKDM2BKDM5C | |
| SCHEMBL25507258 | 0.88 | KDM6A (0.78) | KDM6BKDM6AKDM5BKDM2BKDM5C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025261741-A1 | SYNTHETIC LETHALITY TO TREAT AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE (ADPKD) | ALBERT-LUDWIGS-UNIVERSITAET FREIBURG KOERPERSCHAFT DES OEFFENTLICHEN RECHTS (DE) | 2025-12-26 | — | — | WO | disclosed |
| EP-3664789-B1 | METHODS FOR TREATING DISEASES AND NERVE INJURY | CHILDRENS HOSPITAL MED CT (US) | 2023-11-22 | — | — | EP | disclosed |
| EP-3962559-A1 | METHODS AND COMPOSITIONS FOR TREATING CHRONIC INFLAMMATORY INJURY, METAPLASIA, DYSPLASIA AND CANCERS OF EPITHELIAL TISSUES | University of Houston System (US) | 2022-03-09 | — | — | EP | disclosed |