SCHEMBL29409289

SCHEMBL29409289

Nc1ccc(-c2ccc(N)c([N+](=O)[O-])c2)cc1[N+](=O)[O-]

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 1.00
TDP1 Q9NUW8 5/20 1.00
MEN1 O00255 3/20 1.00
POLB P06746 3/20 1.00
KMT2A Q03164 3/20 1.00
ALDH1A1 P00352 3/20 0.69
CYP3A4 P08684 2/20 0.69
ALOX15 P16050 1/20 0.69
TSHR P16473 2/20 0.64
NPSR1 Q6W5P4 1/20 0.60
LMNA P02545 1/20 0.58
PKM P14618 1/20 0.58
GALR3 O60755 1/20 0.50
THRB P10828 1/20 0.50
CYP1A2 P05177 1/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
GPR35 Q9HC97 1/20 0.47
FFAR4 Q5NUL3 1/20 0.46
MCL1 Q07820 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL737722 1.00 MAPT (1.00) MAPTTDP1MEN1POLBKMT2A
Hydrochloric Acid SCHEMBL3973012 0.96 MAPT (0.92) MAPTTDP1MEN1POLBKMT2A
Hydrochloric Acid SCHEMBL3973011 0.96 MAPT (0.92) MAPTTDP1MEN1POLBKMT2A
SCHEMBL8601406 0.94 MAPT (0.88) MAPTTDP1MEN1POLBKMT2A
SCHEMBL9649469 0.92 TDP1 (0.85) MAPTTDP1MEN1POLBKMT2A
SCHEMBL3178960 0.92 MAPT (0.85) MAPTTDP1MEN1POLBKMT2A
SCHEMBL10714493 0.92 TDP1 (0.85) MAPTTDP1MEN1POLBKMT2A
SCHEMBL30581227 0.92 MAPT (0.85) MAPTTDP1MEN1POLBKMT2A
SCHEMBL30255693 0.90 TDP1 (0.81) MAPTTDP1MEN1POLBKMT2A
SCHEMBL653911 0.90 TDP1 (0.81) MAPTTDP1MEN1POLBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118459695-A Nitro-functionalized polar covalent organic framework material, and preparation method and application thereof 天津大学 2024-08-09 CN claimed
CN-117942953-A Ligand functional magnetic covalent organic framework adsorbent and synthesis method thereof 复旦大学 2024-04-30 CN claimed
CN-115260503-A Preparation method of elastic agent and application of elastic agent in microfluidic chip 苏州量化细胞生物科技有限公司 2022-11-01 CN claimed
CN-121343546-B Temporary bonding adhesive and application thereof 深圳好电科技有限公司 2026-05-12 CN disclosed
WO-2025235718-A1 REINFORCED POLYOXYMETHYLENE POLYMER COMPOSITIONS CELANESE INTERNATIONAL CORPORATION (US) 2025-11-13 WO disclosed
EP-4504812-A1 METHODS FOR CONVERTING SOLID POLYURETHANE ARTICLES BASF SE (DE) 2025-02-12 EP disclosed
CN-118974124-A Method for converting solid polyurethane articles 巴斯夫欧洲公司 2024-11-15 CN disclosed
CN-118027458-B Carbon fiber reinforced polypropylene composite material and preparation method thereof 广东亨嘉橡塑科技有限公司 2024-09-10 CN disclosed
CN-118459695-A Nitro-functionalized polar covalent organic framework material, and preparation method and application thereof 天津大学 2024-08-09 CN disclosed
CN-118459695-A Nitro-functionalized polar covalent organic framework material, and preparation method and application thereof 天津大学 2024-08-09 CN disclosed
WO-2024123797-A1 COMPOSITIONS AND METHODS FOR MODULATING NEURONAL EXCITABILITY THE BROAD INSTITUTE, INC. (US) 2024-06-13 WO disclosed
WO-2023192573-A1 METHODS FOR CONVERTING SOLID POLYURETHANE ARTICLES BASF SE (DE) 2023-10-05 WO disclosed
CN-112654599-B Preparation method of covalent organic framework material and defect repair method 浙江大学 2023-04-28 CN disclosed
CN-110506065-B Thermoplastic polyurethane and composite article 巴斯夫欧洲公司 2023-01-24 CN disclosed
CN-112080484-B Immobilized enzyme based on magnetic COFs, synthetic method and application of immobilized enzyme in preparation of biodiesel 四川大学 2023-01-03 CN disclosed
CN-115487866-A Covalent organic framework material coupled nano metal catalyst and preparation method thereof 浙江大学 2022-12-20 CN disclosed
CN-110612329-B Cut resistant thermoplastic composition 巴斯夫欧洲公司 2022-12-13 CN disclosed
CN-115260503-A Preparation method of elastic agent and application of elastic agent in microfluidic chip 苏州量化细胞生物科技有限公司 2022-11-01 CN disclosed
CN-109923137-B Polyurethane comprising graphene nanostructures 巴斯夫欧洲公司 2022-08-19 CN disclosed
CN-114220957-A Lithium battery negative active material and preparation method and application thereof 格力钛新能源股份有限公司 2022-03-22 CN disclosed