Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 6/20 | 0.54 |
| ▸ | ALK | Q9UM73 | 6/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.48 |
| ▸ | INSR | P06213 | 4/20 | 0.44 |
| ▸ | IGF1R | P08069 | 1/20 | 0.44 |
| ▸ | TTK | P33981 | 2/20 | 0.44 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.43 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22658727 | 1.00 | LRRK2 (0.54) | LRRK2ALKDYRK1AINSRIGF1R | |
| SCHEMBL29409850 | 0.93 | LRRK2 (0.53) | LRRK2ALKDYRK1AINSRIGF1R | |
| SCHEMBL24556858 | 0.93 | LRRK2 (0.53) | LRRK2ALKDYRK1AINSRIGF1R | |
| SCHEMBL24556814 | 0.93 | LRRK2 (0.53) | LRRK2ALKDYRK1AINSRIGF1R | |
| SCHEMBL29409886 | 0.93 | LRRK2 (0.53) | LRRK2ALKDYRK1AINSRIGF1R | |
| SCHEMBL29409918 | 0.92 | LRRK2 (0.64) | LRRK2ALKINSRIGF1RTTK | |
| SCHEMBL24556837 | 0.92 | LRRK2 (0.64) | LRRK2ALKINSRIGF1RTTK | |
| SCHEMBL25107541 | 0.91 | DYRK1A (0.59) | LRRK2ALKDYRK1APTK2 | |
| SCHEMBL22232854 | 0.91 | TTK (0.56) | LRRK2ALKDYRK1ATTKPTK2 | |
| SCHEMBL30199066 | 0.91 | TTK (0.56) | LRRK2ALKDYRK1ATTKPTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3968990-A1 | PYRROLOPYRIMIDINE INHIBITORS OF WILD-TYPE AND MUTANT FORMS OF LRRK2 | Dana-Farber Cancer Institute, Inc. (US) | 2022-03-23 | — | — | EP | disclosed |