Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.35 |
| ▸ | EP300 | Q09472 | 3/20 | 0.35 |
| ▸ | MEF2D | Q14814 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25249510 | 1.00 | KDM1A (0.45) | KDM1AACKR3RXRARXRBRXRG | |
| SCHEMBL25250405 | 1.00 | KDM1A (0.45) | KDM1AACKR3RXRARXRBRXRG | |
| SCHEMBL29410356 | 1.00 | KDM1A (0.45) | KDM1AACKR3RXRARXRBRXRG | |
| SCHEMBL25256819 | 0.91 | ACKR3 (0.42) | KDM1AACKR3RXRARXRBRXRG | |
| SCHEMBL25249882 | 0.89 | ACKR3 (0.41) | KDM1AACKR3RXRARXRBRXRG | |
| SCHEMBL29410364 | 0.89 | ACKR3 (0.41) | KDM1AACKR3RXRARXRBRXRG | |
| SCHEMBL25246315 | 0.89 | ACKR3 (0.41) | KDM1AACKR3RXRARXRBRXRG | |
| SCHEMBL29410330 | 0.89 | ACKR3 (0.41) | KDM1AACKR3RXRARXRBRXRG | |
| SCHEMBL25298988 | 0.89 | ACKR3 (0.42) | KDM1AACKR3RXRARXRBRXRG | |
| SCHEMBL25252295 | 0.89 | ACKR3 (0.42) | KDM1AACKR3RXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4208448-A1 | NOVEL COMPOUNDS | NRG Therapeutics LTD (GB) | 2023-07-12 | — | — | EP | disclosed |
| CN-116096712-A | Novel compounds | NRG治疗有限公司 | 2023-05-09 | — | — | CN | disclosed |
| WO-2022049377-A1 | NOVEL COMPOUNDS | NRG THERAPEUTICS LTD (GB) | 2022-03-10 | — | — | WO | disclosed |