Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 3/20 | 0.43 |
| ▸ | ALB | P02768 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 4/20 | 0.38 |
| ▸ | CA2 | P00918 | 4/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA4 | P22748 | 2/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 7/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 8/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20515159 | 1.00 | CA9 (0.43) | CA9ALBCA1CA2CA12 | |
| SCHEMBL20515160 | 1.00 | CA9 (0.43) | CA9ALBCA1CA2CA12 | |
| SCHEMBL29410424 | 1.00 | CA9 (0.43) | CA9ALBCA1CA2CA12 | |
| SCHEMBL18291960 | 0.95 | CA9 (0.42) | CA9ALBCA1CA2CA12 | |
| SCHEMBL18291963 | 0.94 | CA9 (0.42) | CA9ALBCA1CA2CA12 | |
| SCHEMBL18291997 | 0.94 | CA9 (0.42) | CA9ALBCA1CA2CA12 | |
| SCHEMBL18291987 | 0.93 | CA9 (0.41) | CA9ALBCA1CA2CA12 | |
| SCHEMBL18291989 | 0.93 | CA9 (0.41) | CA9ALBCA1CA2CA12 | |
| SCHEMBL18281367 | 0.93 | CA9 (0.39) | CA9ALBCA1CA2CA12 | |
| SCHEMBL18291996 | 0.93 | CA9 (0.47) | CA9ALBCA1CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3455222-B1 | NUCLEAR IMAGING AND RADIOTHERAPEUTICS AGENTS TARGETING CARBONIC ANHYDRASE IX AND USES THEREOF | UNIV JOHNS HOPKINS (US) | 2022-03-02 | — | — | EP | disclosed |