Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.30 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.30 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29379507 | 1.00 | TSHR (0.39) | TSHRALDH1A1CYP3A4TP53HIF1A | |
| SCHEMBL30422654 | 1.00 | TSHR (0.39) | TSHRALDH1A1CYP3A4TP53HIF1A | |
| SCHEMBL29377110 | 0.96 | TSHR (0.42) | TSHRALDH1A1CYP3A4TP53HIF1A | |
| SCHEMBL2530173 | 0.79 | TSHR (0.43) | TSHRALDH1A1CYP3A4TP53HIF1A | |
| SCHEMBL28125584 | 0.76 | TSHR (0.45) | TSHRALDH1A1CYP3A4TP53HIF1A | |
| SCHEMBL1408198 | 0.76 | TSHR (0.41) | TSHRALDH1A1CYP3A4TP53HIF1A | |
| SCHEMBL29428358 | 0.74 | TSHR (0.44) | TSHRHPGDSMPD1 | |
| SCHEMBL30109516 | 0.73 | CYP4F2 (0.39) | TSHRALDH1A1CYP4F2CYP4A11TDP1 | |
| SCHEMBL29514777 | 0.73 | CYP4F2 (0.39) | TSHRALDH1A1CYP4F2CYP4A11TDP1 | |
| SCHEMBL29396000 | 0.73 | CYP4F2 (0.39) | TSHRALDH1A1CYP4F2CYP4A11TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4153598-A1 | AZACOUMARIN AND AZATHIOCOUMARIN DERIVATIVES FOR USE IN OPTICALLY ACTIVE DEVICES | AMO Ireland (IE) | 2023-03-29 | — | — | EP | disclosed |
| EP-3958788-A1 | SYSTEM AND METHOD | Merck Patent GmbH (DE) | 2022-03-02 | — | — | EP | disclosed |