SCHEMBL29410628

SCHEMBL29410628

O=C(O)COC[C@H]1OC(OCc2ccccc2)[C@H](OCc2ccccc2)[C@@H](OCc2ccccc2)[C@@H]1OCc1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ PTPN1 P18031 10/20 0.56
▸ CDC25B P30305 8/20 0.56
▸ PTPN2 P17706 5/20 0.56
▸ PTPN11 Q06124 5/20 0.56
▸ PTPN6 P29350 4/20 0.56
▸ NT5E P21589 1/20 0.53
▸ SSTR1 P30872 2/20 0.53
▸ SSTR2 P30874 2/20 0.53
▸ SSTR4 P31391 2/20 0.53
▸ SSTR3 P32745 2/20 0.53
▸ SSTR5 P35346 2/20 0.53
▸ CA1 P00915 1/20 0.48
▸ CA2 P00918 1/20 0.48
▸ CA9 Q16790 1/20 0.48
▸ TACR1 P25103 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6229377 0.91 NT5E (0.58) PTPN1CDC25BPTPN2PTPN11PTPN6
SCHEMBL5556044 0.91 NT5E (0.58) PTPN1CDC25BPTPN2PTPN11PTPN6
SCHEMBL6233127 0.91 NT5E (0.58) PTPN1CDC25BPTPN2PTPN11PTPN6
SCHEMBL6232797 0.91 NT5E (0.58) PTPN1CDC25BPTPN2PTPN11PTPN6
SCHEMBL6357791 0.91 NT5E (0.58) PTPN1CDC25BPTPN2PTPN11PTPN6
SCHEMBL8723272 0.91 NT5E (0.58) PTPN1CDC25BPTPN2PTPN11PTPN6
SCHEMBL6232795 0.91 NT5E (0.58) PTPN1CDC25BPTPN2PTPN11PTPN6
SCHEMBL6233124 0.91 NT5E (0.58) PTPN1CDC25BPTPN2PTPN11PTPN6
SCHEMBL6235085 0.90 NT5E (0.59) PTPN1CDC25BPTPN2PTPN11PTPN6
SCHEMBL6235082 0.90 NT5E (0.59) PTPN1CDC25BPTPN2PTPN11PTPN6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116583303-B Tripterine conjugates and uses thereof 瑞阳公司 2026-05-12 — — CN disclosed
CN-116583303-A Tripterine conjugates and uses thereof 瑞阳公司 2023-08-11 — — CN disclosed
EP-4200022-A1 TRIPTOLIDE CONJUGATES AND USES THEREOF Reyoung Corporation (US) 2023-06-28 — — EP disclosed
WO-2022040487-A1 TRIPTOLIDE CONJUGATES AND USES THEREOF REYOUNG CORPORATION (US) 2022-02-24 — — WO disclosed
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