Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.56 |
| ▸ | ACP1 | P24666 | 2/20 | 0.56 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | CRHBP | P24387 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.51 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ENPP2 | Q13822 | 5/20 | 0.50 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.50 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26709452 | 1.00 | PTPN1 (0.56) | PTPN1ACP1AKR1B1MEN1KMT2A | |
| SCHEMBL28979085 | 0.88 | PTPN1 (0.60) | PTPN1ACP1AKR1B1MEN1KMT2A | |
| SCHEMBL26709485 | 0.88 | PTPN1 (0.60) | PTPN1ACP1AKR1B1MEN1KMT2A | |
| SCHEMBL29411713 | 0.88 | PTPN1 (0.60) | PTPN1ACP1AKR1B1MEN1KMT2A | |
| SCHEMBL28978708 | 0.87 | MEN1 (0.57) | PTPN1ACP1MEN1KMT2AALDH1A1 | |
| SCHEMBL28978705 | 0.87 | MEN1 (0.57) | PTPN1ACP1MEN1KMT2AALDH1A1 | |
| SCHEMBL29411679 | 0.87 | MEN1 (0.57) | PTPN1ACP1MEN1KMT2AALDH1A1 | |
| SCHEMBL29411687 | 0.84 | PTPN1 (0.52) | PTPN1ACP1AKR1B1MEN1KMT2A | |
| SCHEMBL28978709 | 0.84 | PTPN1 (0.52) | PTPN1ACP1AKR1B1MEN1KMT2A | |
| SCHEMBL26606778 | 0.84 | PTPN1 (0.52) | PTPN1ACP1AKR1B1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4200286-A1 | COMPOUNDS AND METHODS OF MODULATING 17BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 13 | Metrea Biosciences, Inc. (US) | 2023-06-28 | — | — | EP | disclosed |
| WO-2022040324-A1 | COMPOUNDS AND METHODS OF MODULATING 17β-ΗYDROXYSTEROID DEHYDROGENASE TYPE 13 | METREA BIOSCIENCES, INC. (US) | 2022-02-24 | — | — | WO | disclosed |