Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLCO1B1 | Q9Y6L6 | 5/20 | 0.55 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.55 |
| ▸ | ABCC3 | O15438 | 2/20 | 0.42 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.42 |
| ▸ | SLCO1B3 | Q9NPD5 | 2/20 | 0.42 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19728938 | 1.00 | SLCO1B1 (0.55) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 | |
| SCHEMBL19715709 | 0.90 | SLCO1B1 (0.66) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 | |
| SCHEMBL29411847 | 0.89 | SLCO1B1 (0.55) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 | |
| SCHEMBL29448522 | 0.89 | SLCO1B1 (0.55) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 | |
| SCHEMBL19728880 | 0.89 | SLCO1B1 (0.55) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 | |
| SCHEMBL23697664 | 0.89 | SLCO1B1 (0.55) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 | |
| SCHEMBL29448505 | 0.88 | SLCO1B1 (0.44) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 | |
| SCHEMBL23697214 | 0.88 | SLCO1B1 (0.44) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 | |
| SCHEMBL19728937 | 0.86 | SLCO1B1 (0.58) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 | |
| SCHEMBL29411772 | 0.86 | SLCO1B1 (0.58) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114601830-A | Carbamoyloxymethyltriazolylcyclohexanes as LPA antagonists | 百时美施贵宝公司 | 2022-06-10 | — | — | CN | disclosed |
| CN-109963843-B | Carbamoyloxymethyltriazolylcyclohexanes as LPA antagonists | 百时美施贵宝公司 | 2022-03-11 | — | — | CN | disclosed |