Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLCO1B1 | Q9Y6L6 | 4/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.38 |
| ▸ | ABCC3 | O15438 | 2/20 | 0.38 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.38 |
| ▸ | SLCO1B3 | Q9NPD5 | 2/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MIF | P14174 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19715757 | 1.00 | SLCO1B1 (0.38) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 | |
| SCHEMBL24982985 | 0.90 | SLCO1B1 (0.39) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 | |
| SCHEMBL29068133 | 0.88 | SLCO1B1 (0.37) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 | |
| SCHEMBL25422658 | 0.88 | SLCO1B1 (0.37) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 | |
| SCHEMBL19715601 | 0.88 | SLCO1B1 (0.36) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 | |
| SCHEMBL19715862 | 0.87 | SLCO1B1 (0.32) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 | |
| SCHEMBL25231360 | 0.87 | SLCO1B1 (0.35) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 | |
| SCHEMBL29411775 | 0.87 | SLCO1B1 (0.32) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 | |
| SCHEMBL29068103 | 0.86 | SLCO1B1 (0.36) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 | |
| SCHEMBL30452478 | 0.86 | SLCO1B1 (0.36) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112189010-B | Triazole N-linked carbamoyl cyclohexyl acid as LPA antagonists | 百时美施贵宝公司 | 2026-05-15 | — | — | CN | disclosed |
| EP-3986553-B1 | CYCLOBUTYL CARBOXYLIC ACIDS AS LPA ANTAGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2026-03-25 | — | — | EP | disclosed |
| EP-3986551-B1 | TRIAZOLE CARBOXYLIC ACIDS AS LPA ANTAGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2025-10-29 | — | — | EP | disclosed |
| EP-4452965-A1 | CYCLOHEXANE ACID DERIVATIVES AS LPA RECEPTOR INHIBITORS | Chiesi Farmaceutici S.p.A. (IT) | 2024-10-30 | — | — | EP | disclosed |
| CN-118359590-A | Triazole compound | 上海拓界生物医药科技有限公司 | 2024-07-19 | — | — | CN | disclosed |
| CN-117751106-A | Novel triazole-pyridine substituted pyrrolidinyl and tetrahydro-2H-pyranylacetic acid compounds as LPA antagonists | 唯久生物技术(苏州)有限公司 | 2024-03-22 | — | — | CN | disclosed |
| EP-4330249-A1 | NOVEL TRIAZOLE-PYRIDINE SUBSTITUTED PYRROLIDINYL AND TETRAHYDRO-2H-PYRANYL ACETIC ACID COMPOUNDS AS LPA ANTAGONISTS | Viva Star Biosciences (Suzhou) Co., Ltd. (CN) | 2024-03-06 | — | — | EP | disclosed |
| CN-117460721-A | LPA1 small molecule antagonist | 上海拓界生物医药科技有限公司 | 2024-01-26 | — | — | CN | disclosed |
| CN-112521368-B | Triazole N-linked carbamoyl cyclohexyl acid as LPA antagonists | 百时美施贵宝公司 | 2023-12-05 | — | — | CN | disclosed |
| WO-2023118253-A1 | CYCLOHEXANE ACID DERIVATIVES AS LPA RECEPTOR INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2023-06-29 | — | — | WO | disclosed |
| WO-2022232459-A1 | NOVEL TRIAZOLE-PYRIDINE SUBSTITUTED PYRROLIDINYL AND TETRAHYDRO-2H-PYRANYL ACETIC ACID COMPOUNDS AS LPA ANTAGONISTS | VIVA STAR BIOSCIENCES (SUZHOU) CO., LTD. (CN) | 2022-11-03 | — | — | WO | disclosed |
| CN-114601830-A | Carbamoyloxymethyltriazolylcyclohexanes as LPA antagonists | 百时美施贵宝公司 | 2022-06-10 | — | — | CN | disclosed |
| CN-114599648-A | Triazole carboxylic acids as LPA antagonists | 百时美施贵宝公司 | 2022-06-07 | — | — | CN | disclosed |
| CN-114599641-A | Cyclobutylcarboxylic acids as LPA antagonists | 百时美施贵宝公司 | 2022-06-07 | — | — | CN | disclosed |
| EP-3986551-A1 | TRIAZOLE CARBOXYLIC ACIDS AS LPA ANTAGONISTS | Bristol-Myers Squibb Company (US) | 2022-04-27 | — | — | EP | disclosed |
| EP-3986553-A1 | CYCLOBUTYL CARBOXYLIC ACIDS AS LPA ANTAGONISTS | Bristol-Myers Squibb Company (US) | 2022-04-27 | — | — | EP | disclosed |
| CN-109963843-B | Carbamoyloxymethyltriazolylcyclohexanes as LPA antagonists | 百时美施贵宝公司 | 2022-03-11 | — | — | CN | disclosed |