Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | FAAH | O00519 | 2/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | EPAS1 | Q99814 | 3/20 | 0.41 |
| ▸ | ADH1B | P00325 | 2/20 | 0.35 |
| ▸ | ADH1C | P00326 | 2/20 | 0.35 |
| ▸ | ADH1A | P07327 | 2/20 | 0.35 |
| ▸ | ADH4 | P08319 | 1/20 | 0.35 |
| ▸ | ADH7 | P40394 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.33 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4978224 | 1.00 | TSHR (0.52) | TSHRFAAHTRPV1HIF1ALMNA | |
| SCHEMBL293702 | 1.00 | TSHR (0.52) | TSHRFAAHTRPV1HIF1ALMNA | |
| SCHEMBL536858 | 1.00 | TSHR (0.52) | TSHRFAAHTRPV1HIF1ALMNA | |
| SCHEMBL443450 | 1.00 | TSHR (0.52) | TSHRFAAHTRPV1HIF1ALMNA | |
| SCHEMBL2523320 | 1.00 | TSHR (0.52) | TSHRFAAHTRPV1HIF1ALMNA | |
| SCHEMBL5654128 | 1.00 | TSHR (0.52) | TSHRFAAHTRPV1HIF1ALMNA | |
| SCHEMBL756048 | 1.00 | TSHR (0.52) | TSHRFAAHTRPV1HIF1ALMNA | |
| SCHEMBL15327039 | 1.00 | TSHR (0.52) | TSHRFAAHTRPV1HIF1ALMNA | |
| SCHEMBL21619221 | 1.00 | TSHR (0.52) | TSHRFAAHTRPV1HIF1ALMNA | |
| SCHEMBL9254348 | 1.00 | TSHR (0.52) | TSHRFAAHTRPV1HIF1ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5352689-A | Rhizoxin derivatives and their use as anti-tumor agents | SANKYO COMPANY, LIMITED (JP) | 1994-10-04 | — | — | US | claimed |
| US-4074054-A | Imidazoles and 2-alkyl imidazoles and method for their manufacture | NOBEL HOECHST CHIMIE (FR) | 1978-02-14 | — | — | US | claimed |
| CN-118678955-A | Pharmaceutical composition for preventing and/or treating heart failure | 国立大学法人大阪大学 | 2024-09-20 | — | — | CN | disclosed |
| CN-112204017-B | Benzisoxazole compounds | 国立大学法人大阪大学 | 2024-08-20 | — | — | CN | disclosed |
| CN-117580577-A | Pharmaceutical composition for preventing and/or treating kidney injury and autophagy activator | 国立大学法人大阪大学 | 2024-02-20 | — | — | CN | disclosed |
| CN-111481469-B | copolymer | 宝丽化学工业有限公司 | 2023-09-19 | — | — | CN | disclosed |
| CN-111358713-B | copolymer | 宝丽化学工业有限公司 | 2023-09-19 | — | — | CN | disclosed |
| WO-2023145908-A1 | TWO-LAYER-SEPARATED CLEANSING AGENT COMPOSITION | 味の素株式会社 | 2023-08-03 | — | — | WO | disclosed |
| EP-3394080-B1 | LIPID-LINKED PRODRUGS | UNIV BRITISH COLUMBIA (CA) | 2023-06-07 | — | — | EP | disclosed |
| CN-111329787-B | Copolymer | 宝丽化学工业有限公司 | 2023-03-31 | — | — | CN | disclosed |
| CN-111329788-B | Copolymer | 宝丽化学工业有限公司 | 2023-03-31 | — | — | CN | disclosed |
| CN-1059720-A | Radicicol derivatives, its preparation method and anti-tumor activity thereof | SANKYO CO (JP) | 1992-03-25 | — | — | CN | disclosed |
| WO-1991018905-A1 | RADICICOL DERIVATIVES, THEIR PREPARATION AND THEIR ANTI-TUMOR ACTIVITY | SANKYO COMPANY LIMITED (JP) | 1991-12-12 | — | — | WO | disclosed |
| EP-0460950-A1 | Radicicol derivatives, their preparation and their anti-tumour activity | Sankyo Company Limited (JP) | 1991-12-11 | — | — | EP | disclosed |
| US-5041283-A | Long-chain alkyl trimethylol | KAO CORPORATION (JP) | 1991-08-20 | — | — | US | disclosed |
| EP-0411202-A1 | Cosmetic composition | KAO CORPORATION (JP) | 1991-02-06 | — | — | EP | disclosed |
| EP-0350315-A1 | Rhizoxin derivates and their use as anti-tumor agents | SANKYO COMPANY LIMITED (JP) | 1990-01-10 | — | — | EP | disclosed |
| US-4891363-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | SANKYO COMPANY LIMITED (JP) | 1990-01-02 | — | — | US | disclosed |
| EP-0251827-A2 | New cyclic ether derivatives, their preparation and their use | Sankyo Company Limited (JP) | 1988-01-07 | — | — | EP | disclosed |
| US-4074054-A | Imidazoles and 2-alkyl imidazoles and method for their manufacture | NOBEL HOECHST CHIMIE (FR) | 1978-02-14 | — | — | US | disclosed |