SCHEMBL294158

SCHEMBL294158

CCCCCNC([NH])=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8355975 0.98 EPHX1 (0.67)
SCHEMBL7305201 0.98 EPHX1 (0.67)
SCHEMBL292692 0.98 EPHX1 (0.67)
SCHEMBL3842001 0.98 EPHX1 (0.67)
SCHEMBL7472317 0.98 EPHX1 (0.67)
SCHEMBL7300285 0.98 EPHX1 (0.67)
SCHEMBL8930393 0.98 EPHX1 (0.67)
SCHEMBL4811184 0.98 EPHX1 (0.67)
SCHEMBL10702251 0.98 EPHX1 (0.67)
SCHEMBL42512 0.92

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 190 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11247993-B2 Pyridone derivative, composition and use as antiviral drug thereof JIANGXI CAISHI PHARMACEUTICAL TECHNOLOGY CO., LTD. (CN) 2022-02-15 US claimed
EP-3753936-A1 PYRIDONE DERIVATIVE, COMPOSITION THEREOF AND APPLICATION THEREOF AS ANTI-INFLUENZA DRUG Jiangxi Caishi Pharmaceutical Technology Co., Ltd. (CN) 2020-12-23 EP claimed
EP-3010889-B1 ARYLSULFIDE AND ARYLSULFOXIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES BAYER CROPSCIENCE AG (DE) 2018-10-03 EP claimed
US-8013153-B2 Substituted pyrimidine kinase inhibitors JANSSEN PHARMACEUTICA, N.V. (BE) 2011-09-06 US claimed
WO-2010012793-A1 FUNGICIDE AMINOTHIAZOLE DERIVATIVES BAYER CROPSCIENCE SA (FR) 2010-02-04 WO claimed
US-20090325962-A1 TYROSINE DERIVATIVE GENENTECH, INC. (US) 2009-12-31 US claimed
US-7595399-B2 Tyrosine derivatives GENENTECH, INC. (US) 2009-09-29 US claimed
EP-1435227-B1 Composition for the dyeing of keratinous fibres comprising a direct dye of the monoheteroyldiarylmethane type or a leuco precursor thereof and a dyeing process using it OREAL (FR) 2008-12-03 EP claimed
US-20070254896-A1 SUBSTITUTED PYRIMIDINE KINASE INHIBITORS JANSSEN PHARMACEUTICA, N.V. (BE) 2007-11-01 US claimed
WO-2007109783-A2 SUBSTITUTED PYRIMIDINE KINASE INHIBITORS JANSSEN PHARMACEUTICA, N.V. (BE) 2007-09-27 WO claimed
EP-1194151-A1 INTEGRIN RECEPTOR ANTAGONISTS Merck & Co., Inc. (US) 2002-04-10 EP claimed
EP-1100506-A1 INTEGRIN RECEPTOR ANTAGONISTS Merck & Co., Inc. (US) 2001-05-23 EP claimed
WO-2001021584-A1 TYROSINE DERIVATIVES GENENTECH, INC. (US) 2001-03-29 WO claimed
WO-2000078317-A1 INTEGRIN RECEPTOR ANTAGONISTS MERCK & CO., INC. (US) 2000-12-28 WO claimed
EP-1040111-A1 INTEGRIN RECEPTOR ANTAGONISTS Merck & Co., Inc. (US) 2000-10-04 EP claimed
EP-1040098-A1 INTEGRIN RECEPTOR ANTAGONISTS Merck &amp; Co., Inc. (a New Jersey corp.) (US) 2000-10-04 EP claimed
WO-2000006169-A1 INTEGRIN RECEPTOR ANTAGONISTS MERCK & CO., INC. (US) 2000-02-10 WO claimed
WO-1999031061-A1 INTEGRIN RECEPTOR ANTAGONISTS MERCK & CO., INC. (US) 1999-06-24 WO claimed
WO-1999031099-A1 INTEGRIN RECEPTOR ANTAGONISTS MERCK & CO., INC. (US) 1999-06-24 WO claimed
EP-0056975-B1 WATER SOLUBLE MONOAZOCOMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS DYESTUFFS HOECHST AKTIENGESELLSCHAFT (DE) 1985-01-16 EP claimed