Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCR | P30988 | 5/20 | 0.57 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.54 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.54 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.51 |
| ▸ | ITGAV | P06756 | 1/20 | 0.51 |
| ▸ | CTSL | P07711 | 3/20 | 0.51 |
| ▸ | CTSS | P25774 | 3/20 | 0.51 |
| ▸ | CTSK | P43235 | 3/20 | 0.51 |
| ▸ | CTSH | P09668 | 1/20 | 0.51 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.49 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.49 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.49 |
| ▸ | GLP1R | P43220 | 3/20 | 0.49 |
| ▸ | GCGR | P47871 | 3/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30607444 | 0.87 | CALCR (0.68) | CALCRCRHR1CRHR2KEAP1HCRTR1 | |
| SCHEMBL30432942 | 0.86 | CALCR (0.68) | CALCRCRHR1CRHR2KEAP1GLP1R | |
| SCHEMBL30495679 | 0.85 | CALCR (0.55) | CALCRCRHR1CRHR2CTSLCTSS | |
| SCHEMBL29461520 | 0.85 | CALCR (0.61) | CALCRCRHR1CRHR2ITGB3ITGAV | |
| SCHEMBL30432068 | 0.85 | CALCR (0.66) | CALCRCRHR1CRHR2CALCRLKEAP1 | |
| SCHEMBL30658564 | 0.84 | F2 (0.58) | CALCRCRHR1CRHR2CTSLCTSS | |
| SCHEMBL31182973 | 0.84 | CALCR (0.62) | CALCRCRHR1CRHR2GLP1RGCGR | |
| SCHEMBL30432828 | 0.84 | CALCR (0.59) | CALCRCRHR1CRHR2KEAP1HCRTR1 | |
| SCHEMBL30906485 | 0.84 | CALCR (0.67) | CALCRCRHR1CRHR2HCRTR1HCRTR2 | |
| SCHEMBL31182920 | 0.83 | CALCR (0.71) | CALCRCRHR1CRHR2HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110381984-B | Compositions and methods for improving sexual function | 尼莫克斯股份有限公司 | 2023-11-28 | — | — | CN | disclosed |
| EP-4275688-A2 | METHOD OF AMELIORATING OR PREVENTING THE WORSENING OR THE PROGRESSION OF SYMPTOMS OF BPH | Nymox Corporation (BS) | 2023-11-15 | — | — | EP | disclosed |
| CN-116785403-A | Neurofilament peptides for preventing or slowing the progression of prostate cancer | 尼莫克斯股份有限公司 | 2023-09-22 | — | — | CN | disclosed |
| CN-109310732-B | Neurofilament peptides for preventing or slowing the progression of prostate cancer | 尼莫克斯股份有限公司 | 2023-07-21 | — | — | CN | disclosed |
| CN-114099636-A | Method of treating a condition requiring cell destruction or removal using peptides derived from neurofilament proteins | 尼莫克斯制药公司 | 2022-03-01 | — | — | CN | disclosed |