Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | ENPP1 | P22413 | 3/20 | 0.45 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | AXL | P30530 | 1/20 | 0.35 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.35 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SELE | P16581 | 1/20 | 0.34 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1011889 | 1.00 | PDE4A (0.47) | PDE4APDE4BPDE4CPDE4DENPP1 | |
| SCHEMBL30562904 | 0.84 | PDE4A (0.41) | PDE4APDE4BPDE4CPDE4DENPP1 | |
| SCHEMBL21456839 | 0.84 | PDE4A (0.41) | PDE4APDE4BPDE4CPDE4DENPP1 | |
| SCHEMBL2642415 | 0.84 | PDE4A (0.41) | PDE4APDE4BPDE4CPDE4DENPP1 | |
| SCHEMBL2621720 | 0.84 | PDE4A (0.41) | PDE4APDE4BPDE4CPDE4DENPP1 | |
| SCHEMBL28421484 | 0.84 | MAP4K4 (0.41) | PDE4APDE4BPDE4CPDE4DENPP1 | |
| SCHEMBL282157 | 0.84 | ENPP1 (0.44) | PDE4APDE4BPDE4CPDE4DENPP1 | |
| Hydrochloric Acid SCHEMBL3321635 | 0.83 | PDE4A (0.40) | PDE4APDE4BPDE4CPDE4DENPP1 | |
| SCHEMBL21664277 | 0.81 | PDE4A (0.39) | PDE4APDE4BPDE4CPDE4DENPP1 | |
| SCHEMBL24008957 | 0.80 | ENPP1 (0.63) | ENPP1EGFRKDRFLT4AURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111763214-B | Preparation method of icotinib | 苏州富士莱医药股份有限公司 | 2022-03-15 | — | — | CN | claimed |
| EP-4329755-A1 | EXPANDED DOSAGE REGIMENS FOR INTEGRIN INHIBITORS | Pliant Therapeutics, Inc. (US) | 2024-03-06 | — | — | EP | disclosed |
| CN-117615760-A | Extended dosage regimen for integrin inhibitors | 普利安特治疗公司 | 2024-02-27 | — | — | CN | disclosed |
| CN-115989235-A | Methods of treating respiratory diseases using amino acid compounds | 普利安特治疗公司 | 2023-04-18 | — | — | CN | disclosed |
| EP-4146264-A1 | TREATMENT OF RESPIRATORY DISEASES WITH AMINO ACID COMPOUNDS | Pliant Therapeutics, Inc. (US) | 2023-03-15 | — | — | EP | disclosed |
| WO-2022232838-A1 | EXPANDED DOSAGE REGIMENS FOR INTEGRIN INHIBITORS | PLIANT THERAPEUTICS, INC. (US) | 2022-11-03 | — | — | WO | disclosed |
| CN-111763214-B | Preparation method of icotinib | 苏州富士莱医药股份有限公司 | 2022-03-15 | — | — | CN | disclosed |
| CN-111763214-B | Preparation method of icotinib | 苏州富士莱医药股份有限公司 | 2022-03-15 | — | — | CN | disclosed |