Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | FDPS | P14324 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.41 |
| ▸ | PI4KA | P42356 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | APP | P05067 | 2/20 | 0.40 |
| ▸ | SNCA | P37840 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1943866 | 1.00 | KDM4E (0.53) | KDM4EALDH1A1L3MBTL1FDPSPOLB | |
| SCHEMBL20489915 | 0.95 | KDM4E (0.49) | KDM4EALDH1A1L3MBTL1FDPSPOLB | |
| SCHEMBL29416970 | 0.95 | KDM4E (0.49) | KDM4EALDH1A1L3MBTL1FDPSPOLB | |
| SCHEMBL18810341 | 0.91 | KDM4E (0.51) | KDM4EALDH1A1L3MBTL1FDPSPOLB | |
| SCHEMBL1944149 | 0.88 | KDM4E (0.43) | KDM4EALDH1A1L3MBTL1FDPSPOLB | |
| SCHEMBL20489821 | 0.84 | KDM4E (0.54) | KDM4EALDH1A1L3MBTL1FDPSPOLB | |
| SCHEMBL29417178 | 0.83 | KDM4E (0.50) | KDM4EALDH1A1L3MBTL1FDPSPOLB | |
| SCHEMBL9446790 | 0.83 | KDM4E (0.50) | KDM4EALDH1A1L3MBTL1FDPSPOLB | |
| SCHEMBL21822026 | 0.81 | KDM4E (0.49) | KDM4EALDH1A1L3MBTL1FDPSPOLB | |
| SCHEMBL18809825 | 0.81 | KDM4E (0.49) | KDM4EALDH1A1L3MBTL1FDPSPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112409360-B | Heteroaryl vinyl xanthine derivatives and uses thereof | 广东东阳光药业有限公司 | 2022-12-23 | — | — | CN | disclosed |
| CN-108137513-B | Pyrimidine derivatives | ASKA 制药株式会社 | 2022-03-01 | — | — | CN | disclosed |