Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | UNG | P13051 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 4/20 | 0.40 |
| ▸ | RHOA | P61586 | 1/20 | 0.38 |
| ▸ | FBP1 | P09467 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | P4HB | P07237 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28242748 | 0.83 | TDP1 (0.52) | ALDH1A1TSHRUNGTP53TDP1 | |
| SCHEMBL29055882 | 0.83 | TTR (0.55) | ALDH1A1TSHRUNGTTRFBP1 | |
| Benzene SCHEMBL16487418 | 0.82 | UNG (0.68) | ALDH1A1TSHRUNGTP53TDP1 | |
| SCHEMBL21777904 | 0.82 | UNG (0.68) | ALDH1A1TSHRUNGTP53TDP1 | |
| SCHEMBL1902705 | 0.82 | UNG (0.68) | ALDH1A1TSHRUNGPTGS2TTR | |
| SCHEMBL29373775 | 0.82 | UNG (0.68) | ALDH1A1TSHRUNGTP53TDP1 | |
| SCHEMBL15036 | 0.82 | UNG (0.68) | ALDH1A1TSHRUNGTP53TDP1 | |
| SCHEMBL2164103 | 0.82 | UNG (0.47) | ALDH1A1TSHRUNGTP53TDP1 | |
| SCHEMBL12449045 | 0.82 | TP53 (0.47) | ALDH1A1TSHRUNGTP53TDP1 | |
| Benzoyl Chloride SCHEMBL8178226 | 0.81 | CYP2C19 (0.36) | ALDH1A1TSHRUNGTP53TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024135498-A1 | RESIST COMPOSITION, RESIST PATTERN FORMATION METHOD, AND COMPOUND | 東京応化工業株式会社 | 2024-06-27 | — | — | WO | disclosed |
| US-11820787-B2 | Benfotiamine derivatives in the treatment of alzheimer's disease | SHANGHAI RAISING PHARMACEUTICAL CO., LTD. (CN) | 2023-11-21 | — | — | US | disclosed |
| US-11709427-B2 | Positive resist composition and pattern forming process | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2023-07-25 | — | — | US | disclosed |
| EP-4037687-A1 | BENZOXAZINONE COMPOUNDS AS KLK5/7 DUAL INHIBITORS | Molecular Skin Therapeutics, Inc. (US) | 2022-08-10 | — | — | EP | disclosed |
| US-20210247694-A1 | POSITIVE RESIST COMPOSITION AND PATTERN FORMING PROCESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2021-08-12 | — | — | US | disclosed |
| CN-112933101-A | Benfotiamine derivative, preparation method and pharmaceutical composition thereof | 上海日馨生物科技有限公司 | 2021-06-11 | — | — | CN | disclosed |
| CN-112898342-A | Benfotiamine derivative, preparation method and pharmaceutical composition thereof | 上海日馨生物科技有限公司 | 2021-06-04 | — | — | CN | disclosed |
| US-20210163515-A1 | BENFOTIAMINE DERIVATIVES IN THE TREATMENT OF ALZHEIMER'S DISEASE | SHANGHAI RAISING PHARMACEUTICAL CO., LTD. (CN) | 2021-06-03 | — | — | US | disclosed |
| US-10947258-B1 | Benfotiamine derivatives, method for preparing the same and pharmaceutical composition comprising the same | SHANGHAI RIXIN BIOTECHNOLOGY CO., LTD. (CN) | 2021-03-16 | — | — | US | disclosed |
| CN-109111478-B | Benfotiamine derivative, preparation method and pharmaceutical composition thereof | 上海日馨生物科技有限公司 | 2021-02-26 | — | — | CN | disclosed |
| US-20040220346-A1 | Multi-branched polymer, process for producing the same, and applications thereof | MITSUI CHEMICALS, INC. (JP) | 2004-11-04 | — | — | US | disclosed |
| US-20040191602-A1 | Crosslinkable aromatic resin having protonic acid group, and ion conductive polymer membrane, binder and fuel cell using the resin | MITSUI CHEMICALS, INC. (JP) | 2004-09-30 | — | — | US | disclosed |
| EP-1457511-A1 | CROSSLINKABLE AROMATIC RESINS HAVING PROTONIC ACID GROUPS AND ION CONDUCTIVE POLYMER MEMBRANES BINDERS AND FUEL CELLS MADE BY USING THE SAME | Mitsui Chemicals, Inc. (JP) | 2004-09-15 | — | — | EP | disclosed |
| EP-1457512-A1 | Multi-branched polymer, process for producing the same, and applications thereof | Mitsui Chemicals, Inc. (JP) | 2004-09-15 | — | — | EP | disclosed |
| EP-1396504-A2 | Polyolefin macromonomer, graft polymer obtained from the polyolefin macromonomer, and use thereof | Mitsui Chemicals, Inc. (JP) | 2004-03-10 | — | — | EP | disclosed |
| EP-0768862-B1 | PERSONAL CARE COMPOSITIONS CONTAINING THERMOPLASTIC ELASTOMERIC GRAFT COPOLYMERS | PROCTER & GAMBLE (US) | 2001-10-17 | — | — | EP | disclosed |
| US-6165455-A | Personal care compositions containing thermoplastic elastomeric graft copolymers | THE PROCTER & GAMBLE COMPANY (US) | 2000-12-26 | — | — | US | disclosed |
| US-6041157-A | Environmentally sensitive compositions of matter based on 3H-fluoren-3-ylidenes and process for making same | GOETZ FREDERICK JAMES (US) | 2000-03-21 | — | — | US | disclosed |
| EP-0768862-A1 | PERSONAL CARE COMPOSITIONS CONTAINING THERMOPLASTIC ELASTOMERIC GRAFT COPOLYMERS | THE PROCTER & GAMBLE COMPANY (US) | 1997-04-23 | — | — | EP | disclosed |
| WO-1996000562-A1 | PERSONAL CARE COMPOSITIONS CONTAINING THERMOPLASTIC ELASTOMERIC GRAFT COPOLYMERS | THE PROCTER & GAMBLE COMPANY (US) | 1996-01-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10947258-B1 | Benfotiamine derivatives, method for preparing the same and pharmaceutical composition comprising the same | COMT, BACE1, BACE2 | ALDH1A1 3189/4885TSHR 1203/4885UNG 1838/4885 |
| US-11709427-B2 | Positive resist composition and pattern forming process | EWSR1, PARG, VIM | ALDH1A1 3639/4885TSHR 4671/4885UNG 3468/4885 |
| US-11820787-B2 | Benfotiamine derivatives in the treatment of alzheimer's disease | PSEN2, PSEN1, SLC18A2 | ALDH1A1 1876/4885TSHR 2327/4885UNG 1495/4885 |
| US-20210163515-A1 | BENFOTIAMINE DERIVATIVES IN THE TREATMENT OF ALZHEIMER'S DISEASE | PSEN2, PSEN1, SLC18A2 | ALDH1A1 1876/4885TSHR 2327/4885UNG 1495/4885 |
| US-20210247694-A1 | POSITIVE RESIST COMPOSITION AND PATTERN FORMING PROCESS | EWSR1, PARG, VIM | ALDH1A1 3639/4885TSHR 4671/4885UNG 3468/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.