Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 13/20 | 0.48 |
| ▸ | LCK | P06239 | 1/20 | 0.45 |
| ▸ | DGAT2 | Q96PD7 | 2/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25223228 | 1.00 | BTK (0.48) | BTKLCKDGAT2GPR119NAMPT | |
| SCHEMBL29418739 | 0.95 | BTK (0.46) | BTKLCKDGAT2NAMPT | |
| SCHEMBL29418331 | 0.95 | BTK (0.46) | BTKLCKDGAT2NAMPT | |
| SCHEMBL25238651 | 0.95 | BTK (0.46) | BTKLCKDGAT2NAMPT | |
| SCHEMBL29418480 | 0.91 | BTK (0.48) | BTKLCKDGAT2GPR119NAMPT | |
| SCHEMBL25214221 | 0.91 | BTK (0.48) | BTKLCKDGAT2GPR119NAMPT | |
| SCHEMBL25213824 | 0.89 | BTK (0.48) | BTKLCKDGAT2 | |
| SCHEMBL29418330 | 0.89 | BTK (0.48) | BTKLCKDGAT2 | |
| Hydrochloric Acid SCHEMBL25216874 | 0.87 | BTK (0.52) | BTKLCKDGAT2 | |
| Hydrochloric Acid SCHEMBL29418285 | 0.87 | BTK (0.52) | BTKLCKDGAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116917279-A | BTK inhibitors | 渤健马萨诸塞州股份有限公司 | 2023-10-20 | — | — | CN | disclosed |
| EP-4192587-A1 | BTK INHIBITORS | Biogen MA Inc. (US) | 2023-06-14 | — | — | EP | disclosed |
| WO-2022032019-A1 | BTK INHIBITORS | BIOGEN MA INC. (US) | 2022-02-10 | — | — | WO | disclosed |