Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 15/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | ATR | Q13535 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25223230 | 1.00 | BTK (0.40) | BTKLCKATREGFRJAK3 | |
| SCHEMBL25219282 | 0.92 | BTK (0.42) | BTKLCKATRROCK2DGAT2 | |
| SCHEMBL29418421 | 0.90 | BTK (0.41) | BTKLCKATRDGAT2 | |
| SCHEMBL29418348 | 0.89 | BTK (0.43) | BTKLCKDGAT2 | |
| SCHEMBL25220113 | 0.89 | BTK (0.43) | BTKLCKDGAT2 | |
| SCHEMBL25224087 | 0.89 | BTK (0.41) | BTKLCKATREGFRJAK3 | |
| SCHEMBL29418416 | 0.89 | BTK (0.41) | BTKLCKATREGFRJAK3 | |
| Hydrochloric Acid SCHEMBL25215417 | 0.84 | BTK (0.43) | BTKLCKROCK2 | |
| Hydrochloric Acid SCHEMBL29418469 | 0.84 | BTK (0.43) | BTKLCKROCK2 | |
| Hydrochloric Acid SCHEMBL29418491 | 0.84 | BTK (0.43) | BTKLCKROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4192587-A1 | BTK INHIBITORS | Biogen MA Inc. (US) | 2023-06-14 | — | — | EP | disclosed |
| WO-2022032019-A1 | BTK INHIBITORS | BIOGEN MA INC. (US) | 2022-02-10 | — | — | WO | disclosed |