Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 16/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.36 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29418749 | 1.00 | BTK (0.44) | BTKLCKPIK3CDKIF18AKDM4D | |
| SCHEMBL25240201 | 0.92 | BTK (0.44) | BTKLCKKCNH2 | |
| SCHEMBL29418561 | 0.90 | BTK (0.43) | BTKLCK | |
| SCHEMBL25270137 | 0.90 | BTK (0.43) | BTKLCK | |
| SCHEMBL29418486 | 0.89 | BTK (0.42) | BTKLCKPIK3CDKIF18AKDM4D | |
| SCHEMBL29418564 | 0.89 | BTK (0.42) | BTKLCKPIK3CDKIF18AKDM4D | |
| SCHEMBL29418532 | 0.89 | BTK (0.43) | BTKLCKPIK3CDKIF18AKDM4D | |
| SCHEMBL29418623 | 0.88 | BTK (0.41) | BTKPIK3CDKIF18AKDM4DRET | |
| SCHEMBL29418646 | 0.88 | BTK (0.41) | BTKPIK3CDKIF18AKDM4DRET | |
| SCHEMBL29418556 | 0.87 | PIK3CD (0.40) | BTKLCKPIK3CDKIF18AKDM4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4192587-A1 | BTK INHIBITORS | Biogen MA Inc. (US) | 2023-06-14 | — | — | EP | disclosed |
| WO-2022032019-A1 | BTK INHIBITORS | BIOGEN MA INC. (US) | 2022-02-10 | — | — | WO | disclosed |