Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 16/20 | 0.40 |
| ▸ | DGAT2 | Q96PD7 | 2/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25249361 | 1.00 | BTK (0.40) | BTKDGAT2ROCK2 | |
| SCHEMBL25267962 | 0.92 | BTK (0.42) | BTKDGAT2ROCK2 | |
| SCHEMBL29418625 | 0.91 | BTK (0.41) | BTKDGAT2ROCK2 | |
| SCHEMBL25254803 | 0.91 | BTK (0.41) | BTKDGAT2ROCK2 | |
| SCHEMBL29418646 | 0.90 | BTK (0.41) | BTKDGAT2ROCK2 | |
| SCHEMBL29418623 | 0.90 | BTK (0.41) | BTKDGAT2ROCK2 | |
| SCHEMBL25211202 | 0.89 | BTK (0.38) | BTKDGAT2 | |
| SCHEMBL29418388 | 0.89 | BTK (0.38) | BTKDGAT2 | |
| SCHEMBL25270137 | 0.89 | BTK (0.43) | BTK | |
| SCHEMBL25251063 | 0.89 | BTK (0.41) | BTKDGAT2ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4192587-A1 | BTK INHIBITORS | Biogen MA Inc. (US) | 2023-06-14 | — | — | EP | disclosed |
| WO-2022032019-A1 | BTK INHIBITORS | BIOGEN MA INC. (US) | 2022-02-10 | — | — | WO | disclosed |