Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 20/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29418852 | 0.88 | KRAS (0.49) | KRAS | |
| SCHEMBL29418868 | 0.88 | KRAS (0.49) | KRAS | |
| SCHEMBL30391783 | 0.82 | KRAS (0.43) | KRAS | |
| SCHEMBL30391380 | 0.81 | KRAS (0.42) | KRAS | |
| SCHEMBL25419645 | 0.78 | KRAS (0.40) | KRAS | |
| SCHEMBL29418775 | 0.78 | KRAS (0.40) | KRAS | |
| SCHEMBL30669291 | 0.77 | KRAS (0.44) | KRAS | |
| SCHEMBL30600191 | 0.76 | KRAS (0.71) | KRAS | |
| SCHEMBL31691620 | 0.75 | KRAS (0.51) | KRAS | |
| Trifluoroacetic Acid SCHEMBL30391092 | 0.73 | KRAS (0.38) | KRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4192585-A1 | KRAS G12D INHIBITORS | Mirati Therapeutics, Inc. (US) | 2023-06-14 | — | — | EP | disclosed |
| WO-2022031678-A1 | KRAS G12D INHIBITORS | Mirati Therapeutics, Inc. (US) | 2022-02-10 | — | — | WO | disclosed |