Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 20/20 | 0.63 |
| ▸ | JAK2 | O60674 | 7/20 | 0.60 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2239185 | 1.00 | NTRK1 (0.63) | NTRK1JAK2NTRK3 | |
| SCHEMBL23178521 | 1.00 | NTRK1 (0.63) | NTRK1JAK2NTRK3 | |
| SCHEMBL2239181 | 1.00 | NTRK1 (0.63) | NTRK1JAK2NTRK3 | |
| SCHEMBL30460146 | 0.90 | NTRK1 (0.60) | NTRK1JAK2NTRK3 | |
| SCHEMBL2599310 | 0.89 | NTRK1 (0.51) | NTRK1JAK2NTRK3 | |
| SCHEMBL2599314 | 0.89 | NTRK1 (0.51) | NTRK1JAK2NTRK3 | |
| SCHEMBL30534196 | 0.87 | NTRK1 (0.56) | NTRK1JAK2NTRK3 | |
| SCHEMBL22097353 | 0.87 | NTRK1 (0.48) | NTRK1JAK2NTRK3 | |
| SCHEMBL460919 | 0.84 | NTRK1 (0.62) | NTRK1JAK2 | |
| SCHEMBL460918 | 0.84 | NTRK1 (0.62) | NTRK1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120230105-A | Preparation method of larotinib intermediate | 浙江美诺华药物化学有限公司 | 2025-07-01 | — | — | CN | disclosed |
| CN-109414442-B | Liquid preparation of compound | 洛克索肿瘤学股份有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-114163445-A | Raatinib intermediate and preparation method thereof | 重庆医科大学 | 2022-03-11 | — | — | CN | disclosed |